Lectures

The PDF files of the lectures presented during the course are reproduced here with the kind permission of the individual lecturers. This material is provided for educational use only. The information in these slides including all data, images and related materials are the property of the individual lecturer. No part of this material may be reproduced without explicit written permission from the lecturer.

In many cases, two versions of the slides from a lecture are provided. The "1up" version contains one slide per page and is suitable for online viewing, while the "6up" version has 6 slides per page, suitable for printing. A copy of the original PowerPoint slides may also be provided, in cases where there is animation that would not be viewable in PDF format.

Note that 3 of the talks from November 3, 2005, failed to get recorded. The slides for those talks are provided below, but not the audio. There were similar talks given as part of the 2003 CryoEM course.

Instructor	Lectures	Slides (*.pdf)	Audio (*.mp3)
Bridget Carragher Department of Cell Biology, CB129 The Scripps Research Institute, 10550 North Torrey Pines Road La Jolla, CA 92037, USA Tel: (858) 784-9050 Fax: (858) 784-9090	November 2, 2005: + Welcome	PDF 1up, 557K PDF 6up, 244	3 MB
Ron Milligan Department of Cell Biology The Scripps Research Institute 10550 North Torrey Pines Road La Jolla, CA 92037, USA Tel: (858) 784- 9827 Fax: (858) 784- 2749	November 2, 2005: + Introduction & Course Overview	Slides not publicly available. Please request these directly from the instructor.	8.7 MB
Mark Yeager Department of Cell Biology The Scripps Research Institute 10550 North Torrey Pines Road La Jolla, CA 92037, USA Tel: (858) 784-8584 Fax: (858) 784-2504	November 2, 2005: + General Overview of Molecular Microscopy	Slides not publicly available. Please request these directly from the instructor.	38.5 MB
Wah Chiu Departments of Biochemistry & Molecular Biology Baylor College of Medicine One Baylor Plaza Houston, TX, 77030 Tel: (713) 798-5734 Fax: (713) 798-1625	November 2, 2005: + Molecular Microscopy: Past, Present and Future	PDF 1up, 46M PDF 6up, 16M	33 MB
Robert M. Glaeser Department of Molecular & Cell Biology University of California, Berkeley 239 Hildebrand Hall 3206 Berkeley, CA 94720-3206 Tel: (510) 642-2905 Fax: (510) 486-6488	November 3, 2005: + Fundamentals of Electron Microscopy: Theory	PDF 1up, 11M PDF 6up, 9.8M	recording unavailable
Ron Milligan Department of Cell Biology The Scripps Research Institute 10550 North Torrey Pines Road La Jolla, CA 92037, USA Tel: (858) 784- 9827 Fax: (858) 784- 2749	November 3, 2005: + Cryo-specimen Preparation	Slides not publicly available. Please request these directly from the instructor.	recording unavailable
David de Rosier Brandeis University 415 South Street Waltham, MA 02454 Tel: (781) 736-2494 Fax: (781) 736-2405	November 3, 2005: + Fundamentals of Fourier Theory	PowerPoint, 3.4M PDF 1up, 5.0M PDF 6up, 4.1M	recording unavailable
Phil Mercurio Department of Cell Biology The Scripps Research Institute 10550 North Torrey Pines Road La Jolla, CA 92037, USA Tel: (858) 784-9040 Fax: (858) 784-9090	November 3, 2005: + Introduction to Linux (2 parts)	PDF 1up, 2.9M PDF 6up, 920K	23 MB 18 MB
Vincenz Unger Department of molecular Biophysics and Biochemistry Yale University P.O. Box 208024 New Haven, CT 06520-8024 Tel: (203) 785-5652 Fax: (203) 785-6404	November 4, 2005: + Introduction to 2D Crystal Analysis	PDF 1up, 14M PDF 6up, 8.4M	35 MB
Yoshinori Fujiyoshi Department of Biophysics Faculty of Science Kyoto University Phone: 81-75-753-4215 Fax: 81-75-753-4218	November 4, 2005: + High Resolution CryoEM	Slides not publicly available. Please request these directly from the instructor.	33 MB
Ron Milligan Department of Cell Biology The Scripps Research Institute 10550 North Torrey Pines Road La Jolla, CA 92037, USA Tel: (858) 784- 9827 Fax: (858) 784- 2749	November 4, 2005: + Diffraction Quiz	Slides not publicly available. Please request these directly from the instructor.	21 MB
David de Rosier Brandeis University 415 South Street Waltham, MA 02454 Tel: (781) 736-2494 Fax: (781) 736-2405	November 5, 2005: + Introduction to Helical Analysis	PowerPoint, 5.3M PDF 1up, 6.4M PDF 6up, 2.4M	30 MB
Tim Baker Departments of Chemistry & Biochemistry University of California, San Diego 9500 Gilman Drive 0378 La Jolla, California 92093-0378 Tel: (858)-534-5845	November 5, 2005: + Introduction to Icosahedral Virus Analysis	PDF 1up, 28M PDF 6up, 18M	48 MB
Joachim Frank Wadsworth Center Empire State Plaza P.O. Box 509 Albany, New York 12201-0509 Tel: (518) 474-7002	November 6, 2005: + Introduction to Single Particle Analysis	PDF 1up, 12M PDF 6up, 4.7M	41 MB
Niko Grigorieff MS 029, Rosenstiel Center Brandeis University 415 South St. Waltham MA 02454-9110 Phone 781-736-2444 Fax: 781-736-2419	November 6, 2005: + Refinement Strategies for Single Particle Structure Determination	PDF 1up, 9.8M PDF 6up, 5.2M	32 MB
Pawel Penczek Department of Biochemistry and Molecular Biology University of Texas-Houston Medical School P.O. Box 20708 Houston, Texas 77225 Tel: (713) 500-5416 Fax: (713) 500-0652	November 7, 2005: + Image Assessment	PDF 1up, 2.1M PDF 6up, 840K	35 MB
Steven Ludtke National Center for Macromolecular Imaging Baylor College of Medicine Houston, Texas 77030 Tel: (713) 798 -6989 Fax: (713) 798-1625	November 7, 2005: + SP Reconstruction: Strategies for High Resolution	PDF 1up, 5.2M PDF 6up, 4.9M	37 MB
Michael G. Rossmann Dept. of Biological Sciences Purdue University 915 W. State Street West Lafayette, IN 47907, USA Tel: 765-494-4911 Fax: 765-496-1189	November 7, 2005: + Fitting High Resolution Structures into Low Resolution EM Maps	PDF 1up, 9.7M PDF 6up, 4.0M	33 MB
Clint Potter Department of Cell Biology, CB129 The Scripps Research Institute, 10550 North Torrey Pines Road La Jolla, CA 92037, USA Tel: (858) 784-9050 Fax: (858) 784-9090	November 8, 2005: + Automation 1	PDF 1up, 43M PDF 6up, 15M	15 MB
Bridget Carragher Department of Cell Biology, CB129 The Scripps Research Institute, 10550 North Torrey Pines Road La Jolla, CA 92037, USA Tel: (858) 784-9050 Fax: (858) 784-9090	November 8, 2005: + Automation 2	PDF 1up, 33M PDF 6up, 14M	16 MB
Scott Stagg Department of Cell Biology The Scripps Research Institute 10550 North Torrey Pines Road La Jolla, CA 92037, USA Tel: (858) 784-9208 Fax: (858) 784-9090	November 8, 2005: + Automation In Practice	PDF 1up, 7.1M PDF 6up, 1.5M	18 MB
Niels Volkmann The Burnham Institute 10901 North Torrey Pines Road La Jolla, CA 92037 Tel: (858) 646-3187 Fax: (858) 646-3195	November 9, 2005: + EM Fitting	PDF 1up, 982K PDF 6up, 1.1M	23 MB
Charles L. Brooks, III Department of Molecular Biology The Scripps Research Institute 10550 North Torrey Pines Road La Jolla, CA 92037, USA Tel: (858) 784-8035 Fax: (858) 784- 8688	November 9, 2005: + NMFF: Flexible Fitting of Atomic Structures into Low-Resolution EM Maps	PDF 1up, 25M PDF 6up, 12M	24 MB
Michel Sanner Department of Molecular Biology The Scripps Research Institute 10550 North Torrey Pines Road La Jolla, CA 92037, USA Tel: (858) 784-2341 Fax: (858) 784-2860	November 9, 2005: + Multi-Modal Visualization of Macromolecular Assemblies Using Python	Slides not publicly available. Please request these directly from the instructor.	13 MB
Catherine L. Lawson Department of Chemistry and Chemical Biology Rutgers University 610 Taylor Road Piscataway, NJ 08854 Tel: 732 445 8074 Fax: 732 445 5312	November 9, 2005: + Deposition and Retrieval of CryoEM Structure Data	PDF 1up, 8.3M PDF 6up, 2.4M	12 MB
Nicolas Boisset Laboratoire de Min�ralogie Cristallographie Case 115 140 Rue de Lourmel 75015 Paris, France Tel: +33 (0) 1 44 27 45 85 Fax: +33 (0) 1 44 27 37 85	November 10, 2005: + Random Conical Tilt	PDF 1up, 5.2M PDF 6up, 4.9M	22 MB