2012 Workshop

A Workshop on Advanced Topics in EM Structure Determination: Optimization and Validation

November 11-16, 2012

A major goal of the workshop will be to discuss some of the challenges that we face in using cryoEM to solve the structure of macromolecules.  Topics to be discussed will include improvements in specimen preparation, imaging, processing and reconstruction, and methods for validation. The workshop is aimed at students, postdocs and faculty that already have some experience practicing cryoEM. The basic format of the course will be theoretical lectures in the mornings followed by practical lectures and demonstrations and panel discussions in the afternoon. Evenings will be reserved for poster presentations by participants and research talks by instructors.

The instructors for the course  included: David Agard (UCSF), Bridget Carragher (TSRI), Yifan Cheng (UCSF), Anchi Cheng (TSRI), Wah Chiu (Baylor), David DeRosier (Brandeis), Joachim Frank (Columbia), Bob Glaeser (LBL), Niko Grigorieff (Brandeis), Richard Henderson (MRC), Tilak Jain (TSRI), Debbie Kelly (Virigina Tech.), Werner Kuhlbrandt (MPI), Gabe Lander (Berkeley), Steve Ludtke (Baylor), Ron Milligan (TSRI), Pawel Penczek (U. Texas), Clint Potter (TSRI), John Rubinstein (Toronto), Andrej Sali (UCSF), Sjors Scheres (MRC), Holger Stark (MPI), Elizabeth Villa (MPI), Tom Walz (Harvard), Ian WIlson (TSRI).

The  agenda can be viewed here.

The lectures presented during the course can be viewed here.

The course photo is available here.

For other inquiries send email to:  nramm_workshop@scripps.edu

Bridget Carragher, Clinton S. Potter and Ronald A. Milligan

National Resource for Automated Molecular Microscopy,

The Scripps Research Institute

The National Resource for Automated Molecular Microscopy is supported by grants from the National Institutes of Health’s National Center for Research Resources RR017573) and National Institute of General Medical Sciences (GM103310).