Publications

2022 (25)

  1. Andrews SF, Raab JE, Gorman J, Gillespie RA, Cheung CSF, Rawi R, Cominsky LY, Boyington JC, Creanga A, Shen CH, Harris DR, Olia AS, Nazzari AF, Zhou T, Houser KV, Chen GL, Mascola JR, Graham BS, Kanekiyo M, Ledgerwood JE, Kwong PD, McDermott AB. A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination. Nat Med. 2022;28(2):373-382.
  2. Ashraf KU, Nygaard R, Vickery ON, Erramilli SK, Herrera CM, McConville TH, Petrou VI, Giacometti SI, Dufrisne MB, Nosol K, Zinkle AP, Graham CLB, Loukeris M, Kloss B, Skorupinska-Tudek K, Swiezewska E, Roper DI, Clarke OB, Uhlemann AC, Kossiakoff AA, Trent MS, Stansfeld PJ, Mancia F. Structural basis of lipopolysaccharide maturation by the O-antigen ligase. Nature. 2022;604(7905):371-376.
  3. Cao X, Boyaci H, Chen J, Bao Y, Landick R, Campbell EA. Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile. Nature. 2022.
  4. Capper MJ, Yang S, Stone AC, Vatansever S, Zilberg G, Mathiharan YK, Habib R, Hutchinson K, Schlessinger A, Mezei M, Osman R, Zhang B, Wacker D. Substrate Binding and Inhibition of the Anion Exchanger 1 Transporter. bioRxiv. 2022. [preprint]
  5. Chen J, Wang Q, Malone B, Llewellyn E, Pechersky Y, Maruthi K, Eng ET, Perry JK, Campbell EA, Shaw DE, Darst SA. Ensemble cryo-EM reveals conformational states of the nsp13 helicase in the SARS-CoV-2 helicase replication-transcription complex. Nat Struct Mol Biol. 2022;29(3):250-260.
  6. Cheung CS, Gorman J, Andrews SF, Rawi R, Reveiz M, Shen CH, Wang Y, Harris DR, Nazzari AF, Olia AS, Raab J, Teng IT, Verardi R, Wang S, Yang Y, Chuang GY, McDermott AB, Zhou T, Kwong PD. Structure of an influenza group 2-neutralizing antibody targeting the hemagglutinin stem supersite. Structure. 2022.
  7. Chua EYD, Mendez JH, Rapp M, Ilca SL, Zi Tan Y, Maruthi K, Kuang H, Zimanyi CM, Cheng A, Eng ET, Noble AJ, Potter CS, Carragher B. Better, Faster, Cheaper: Recent Advances in Cryo-Electron Microscopy. Annu Rev Biochem. 2022.
  8. De Gasperi R, Mo C, Azulai D, Wang Z, Harlow LM, Du Y, Graham Z, Pan J, Liu Xh, Guo L. Numb is required for optimal contraction of skeletal muscle. Journal of Cachexia, Sarcopenia and Muscle. 2022.
  9. Falzone ME, Feng Z, Alvarenga OE, Pan Y, Lee B, Cheng X, Fortea E, Scheuring S, Accardi A. TMEM16 scramblases thin the membrane to enable lipid scrambling. Nat Commun. 2022;13(1):2604.
  10. Gorman J, Cheung CS-F, Duan Z, Sun Y, Wang P, Boyington JC, Biju A, Bylund T, Cheng C, Ou L, Stephens T, Tsybovsky Y, Verardi R, Wang S, Yang Y, Zhang B, Zheng C, Zhou T, Mascola JR, Ho DD, Ho M, Kwong PD. Prefusion-Stabilized Lassa Virus Trimer Identifies Neutralizing Nanobodies and Reveals an Apex-Situated Site of Vulnerability. bioRxiv. 2022:2022.2004.2021.488985.
  11. Han B, Takvorian PM, Weiss LM. The Function and Structure of the Microsporidia Polar Tube. Exp Suppl. 2022;114:179-213.
  12. Hunter B, Benoit MPMH, Asenjo AB, Doubleday C, Trofimova D, Sosa H, Allingham JS. Kinesin-8-specific loop-2 controls the dual activities of the motor domain according to tubulin protofilament shape. bioRxiv. 2022. [preprint]
  13. Kelley K, Raczkowski AM, Klykov O, Jaroenlak P, Bobe D, Kopylov M, Eng ET, Bhabha G, Potter CS, Carragher B, Noble AJ. Waffle Method: A general and flexible approach for improving throughput in FIB-milling. Nat Commun. 2022;13(1):1857.
  14. Klykov O, Kopylov M, Carragher B, Heck AJR, Noble AJ, Scheltema RA. Label-free visual proteomics: Coupling MS- and EM-based approaches in structural biology. Mol Cell. 2022;82(2):285-303.
  15. Liang WG, Wijaya J, Wei H, Noble AJ, Mancl JM, Mo S, Lee D, Lin King JV, Pan M, Liu C, Koehler CM, Zhao M, Potter CS, Carragher B, Li S, Tang WJ. Structural basis for the mechanisms of human presequence protease conformational switch and substrate recognition. Nat Commun. 2022;13(1):1833.
  16. Malik R, Johnson RE, Prakash L, Prakash S, Ubarretxena-Belandia I, Aggarwal AK. Cryo-EM structure of translesion DNA synthesis polymerase zeta with a base pair mismatch. Nat Commun. 2022;13(1):1050.
  17. Malone BF, Perry JK, Olinares PDB, Chen J, Appelby TK, Feng JY, Bilello JP, Ng H, Sotiris J, Ebrahim M, Chua EYD, Mendez JH, Eng ET, Landick R, Chait BT, Campbell EA, Darst SA. Structural basis for substrate selection by the SARS-CoV-2 replicase. bioRxiv. 2022:2022.2005.2020.492815.
  18. Puno MR, Lima CD. Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex. Cell. 2022;185(12):2132-2147 e2126.
  19. Rashid A, Tevlin M, Lu Y, Shaham S. A developmental pathway for epithelial-to-motoneuron transformation in C. elegans. bioRxiv. 2022:2022.2005.2027.493712.
  20. Reddy KD, Ciftci D, Scopelliti AJ, Boudker O. The archaeal glutamate transporter homologue GltPh shows heterogeneous substrate binding. J Gen Physiol. 2022;154(5):e202213131.
  21. Selvakumar P, Fernández-Mariño AI, Khanra N, He C, Paquette AJ, Wang B, Huang R, Smider VV, Rice WJ, Swartz KJ, Meyerson JR. Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators. bioRxiv. 2022:2022.2004.2019.488765.
  22. Vallese F, Kim K, Yen LY, Johnston JD, Noble AJ, Calì T, Clarke OB. Architecture of the human erythrocyte ankyrin-1 complex. bioRxiv. 2022. [preprint]
  23. Zheng X, Hu Z, Li H, Yang J. Structure of the human cone photoreceptor cyclic nucleotide-gated channel. Nat Struct Mol Biol. 2022;29(1):40-46.
  24. Zheng X, Li H, Hu Z, Su D, Yang J. Structural and functional characterization of an achromatopsia-associated mutation in a phototransduction channel. Commun Biol. 2022;5(1):190.
  25. Zhou T, Chen L, Gorman J, Wang S, Kwon YD, Lin BC, Louder MK, Rawi R, Stancofski ED, Yang Y, Zhang B, Quigley AF, McCoy LE, Rutten L, Verrips T, Weiss RA, Program VRCP, Doria-Rose NA, Shapiro L, Kwong PD. Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site. Structure. 2022.

2021 (36)

  1. Accardi A, Falzone M, Feng Z, Alvarenga O, Pang Y, Lee B, Cheng X, Fortea E, Scheuring S. TMEM16 scramblases thin the membrane to enable lipid scrambling. Nature Portfolio. 2021. [preprint]
  2. Alegre KO, Paknejad N, Su M, Lou JS, Huang J, Jordan KD, Eng ET, Meyerson JR, Hite RK, Huang XY. Structural basis and mechanism of activation of two different families of G proteins by the same GPCR. Nat Struct Mol Biol. 2021;28(11):936-944.
  3. Alink LM, Eng ET, Gheorghita R, Rice W, Cheng A, Carragher B, Potter CS. System Environmental Metrics Collector for EM facilities. bioRxiv. 2021. [preprint]
  4. Benoit M, Asenjo AB, Paydar M, Dhakal S, Kwok BH, Sosa H. Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14. Nat Commun. 2021;12(1):3637.
  5. Budell WC, Allegri L, Dandey V, Potter CS, Carragher B. Cryo-Electron Microscopic Grid Preparation for Time-Resolved Studies using a Novel Robotic System, Spotiton. J Vis Exp. 2021(168):e62271.
  6. Cater RJ, Chua GL, Erramilli SK, Keener JE, Choy BC, Tokarz P, Chin CF, Quek DQY, Kloss B, Pepe JG, Parisi G, Wong BH, Clarke OB, Marty MT, Kossiakoff AA, Khelashvili G, Silver DL, Mancia F. Structural basis of omega-3 fatty acid transport across the blood-brain barrier. Nature. 2021;595(7866):315-319.
  7. Cerutti G, Guo Y, Zhou T, Gorman J, Lee M, Rapp M, Reddem ER, Yu J, Bahna F, Bimela J, Huang Y, Katsamba PS, Liu L, Nair MS, Rawi R, Olia AS, Wang P, Zhang B, Chuang GY, Ho DD, Sheng Z, Kwong PD, Shapiro L. Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host Microbe. 2021:2021.2001.2010.426120.
  8. Chen Y, Xu K, Piccoli L, Foglierini M, Tan J, Jin W, Gorman J, Tsybovsky Y, Zhang B, Traore B, Silacci-Fregni C, Daubenberger C, Crompton PD, Geiger R, Sallusto F, Kwong PD, Lanzavecchia A. Structural basis of malaria RIFIN binding by LILRB1-containing antibodies. Nature. 2021;592(7855):639-643.
  9. Cheng A, Negro C, Bruhn JF, Rice WJ, Dallakyan S, Eng ET, Waterman DG, Potter CS, Carragher B. Leginon: New features and applications. Protein Sci. 2021;30(1):136-150.
  10. Chuang G-Y, Shen C-H, Cheung CS-F, Gorman J, Creanga A, Joyce MG, Leung K, Rawi R, Wang L, Yang ES, Yang Y, Zhang B, Zhang Y, Kanekiyo M, Zhou T, DeKosky BJ, Graham BS, Mascola JR, Kwong PD. Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses. Frontiers in Immunology. 2021;12(1725).
  11. Grau D, Zhang Y, Lee CH, Valencia-Sanchez M, Zhang J, Wang M, Holder M, Svetlov V, Tan D, Nudler E, Reinberg D, Walz T, Armache KJ. Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction. Nat Commun. 2021;12(1):714.
  12. Grossman-Haham I, Coudray N, Yu Z, Wang F, Zhang N, Bhabha G, Vale RD. Structure of the radial spoke head and insights into its role in mechanoregulation of ciliary beating. Nat Struct Mol Biol. 2021;28(1):20-28.
  13. Herrera NG, Morano NC, Celikgil A, Georgiev GI, Malonis RJ, Lee JH, Tong K, Vergnolle O, Massimi AB, Yen LY, Noble AJ, Kopylov M, Bonanno JB, Garrett-Thomson SC, Hayes DB, Bortz RH, 3rd, Wirchnianski AS, Florez C, Laudermilch E, Haslwanter D, Fels JM, Dieterle ME, Jangra RK, Barnhill J, Mengotto A, Kimmel D, Daily JP, Pirofski LA, Chandran K, Brenowitz M, Garforth SJ, Eng ET, Lai JR, Almo SC. Characterization of the SARS-CoV-2 S Protein: Biophysical, Biochemical, Structural, and Antigenic Analysis. ACS Omega. 2021;6(1):85-102.
  14. Hsia Y, Mout R, Sheffler W, Edman NI, Vulovic I, Park YJ, Redler RL, Bick MJ, Bera AK, Courbet A, Kang A, Brunette TJ, Nattermann U, Tsai E, Saleem A, Chow CM, Ekiert D, Bhabha G, Veesler D, Baker D. Design of multi-scale protein complexes by hierarchical building block fusion. Nat Commun. 2021;12(1):2294.
  15. Khanra N, Brown PM, Perozzo AM, Bowie D, Meyerson JR. Architecture and structural dynamics of the heteromeric GluK2/K5 kainate receptor. Elife. 2021;10.
  16. Kim K, Kopylov M, Bobe D, Kelley K, Eng ET, Arvan P, Clarke OB. The structure of natively iodinated bovine thyroglobulin. Acta Crystallogr D Struct Biol. 2021;77(Pt 11):1451-1459.
  17. Kim PT, Noble AJ, Cheng A, Bepler T. Learning to automate cryo-electron microscopy data collection with Ptolemy. arXiv preprint arXiv:211201534. 2021.
  18. Kwon YD, Asokan M, Gorman J, Zhang B, Liu Q, Louder MK, Lin BC, McKee K, Pegu A, Verardi R, Yang ES, Program VP, Carlton K, Doria-Rose NA, Lusso P, Mascola JR, Kwong PD. A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention. MAbs. 2021;13(1):1946918.
  19. Lee IH, Procko C, Lu Y, Shaham S. Stress-Induced Neural Plasticity Mediated by Glial GPCR REMO-1 Promotes C. elegans Adaptive Behavior. Cell reports. 2021;34(2):108607.
  20. Lee M, Changela A, Gorman J, Rawi R, Bylund T, Chao CW, Lin BC, Louder MK, Olia AS, Zhang B, Doria-Rose NA, Zolla-Pazner S, Shapiro L, Chuang GY, Kwong PD. Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces. Nat Commun. 2021;12(1):6470.
  21. Liou SH, Singh SK, Singer RH, Coleman RA, Liu WL. Structure of the p53/RNA polymerase II assembly. Commun Biol. 2021;4(1):397.
  22. Malone B, Chen J, Wang Q, Llewellyn E, Choi YJ, Olinares PDB, Cao X, Hernandez C, Eng ET, Chait BT, Shaw DE, Landick R, Darst SA, Campbell EA. Structural basis for backtracking by the SARS-CoV-2 replication-transcription complex. Proc Natl Acad Sci U S A. 2021;118(19).
  23. Mei L, Reynolds MJ, Garbett D, Gong R, Meyer T, Alushin GM. Structural mechanism for bi-directional actin crosslinking by T-plastin. bioRxiv. 2021:2021.2012.2007.471696. [preprint]
  24. Olinares PDB, Kang JY, Llewellyn E, Chiu C, Chen J, Malone B, Saecker RM, Campbell EA, Darst SA, Chait BT. Native Mass Spectrometry-Based Screening for Optimal Sample Preparation in Single-Particle Cryo-EM. Structure. 2021;29(2):186-195 e186.
  25. Rapp M, Guo Y, Reddem ER, Yu J, Liu L, Wang P, Cerutti G, Katsamba P, Bimela JS, Bahna FA, Mannepalli SM, Zhang B, Kwong PD, Huang Y, Ho DD, Shapiro L, Sheng Z. Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class. Cell reports. 2021;35(1):108950.
  26. Reddy KD, Ciftci D, Scopelliti A, Boudker O. Heterogeneous substrate binding in a glutamate transporter homologue. bioRxiv. 2021. [preprint].
  27. Roark RS, Li H, Williams WB, Chug H, Mason RD, Gorman J, Wang S, Lee FH, Rando J, Bonsignori M, Hwang KK, Saunders KO, Wiehe K, Moody MA, Hraber PT, Wagh K, Giorgi EE, Russell RM, Bibollet-Ruche F, Liu W, Connell J, Smith AG, DeVoto J, Murphy AI, Smith J, Ding W, Zhao C, Chohan N, Okumura M, Rosario C, Ding Y, Lindemuth E, Bauer AM, Bar KJ, Ambrozak D, Chao CW, Chuang GY, Geng H, Lin BC, Louder MK, Nguyen R, Zhang B, Lewis MG, Raymond D, Doria-Rose NA, Schramm CA, Douek DC, Roederer M, Kepler TB, Kelsoe G, Mascola JR, Kwong PD, Korber BT, Harrison SC, Haynes BF, Hahn BH, Shaw GM. Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science. 2020:2020.2008.2005.237693.
  28. Ruijgrok PV, Ghosh RP, Zemsky S, Nakamura M, Gong R, Ning L, Chen R, Vachharajani VT, Chu AE, Anand N, Eguchi RR, Huang PS, Lin MZ, Alushin GM, Liphardt JT, Bryant Z. Optical control of fast and processive engineered myosins in vitro and in living cells. Nat Chem Biol. 2021.
  29. Saecker RM, Chen J, Chiu CE, Malone B, Sotiris J, Ebrahim M, Yen LY, Eng ET, Darst SA. Structural origins of Escherichia coli RNA polymerase open promoter complex stability. bioRxiv. 2021. [preprint].
  30. Saponaro A, Bauer D, Giese MH, Swuec P, Porro A, Gasparri F, Sharifzadeh AS, Chaves-Sanjuan A, Alberio L, Parisi G, Cerutti G, Clarke OB, Hamacher K, Colecraft HM, Mancia F, Hendrickson WA, Siegelbaum SA, DiFrancesco D, Bolognesi M, Thiel G, Santoro B, Moroni A. Gating movements and ion permeation in HCN4 pacemaker channels. Mol Cell. 2021;81(14):2929-2943 e2926.
  31. Selvakumar P, Lee J, Khanra N, He C, Munguba H, Kiese L, Broichhagen J, Reiner A, Levitz J, Meyerson JR. Structural and compositional diversity in the kainate receptor family. Cell reports. 2021;37(4):109891.
  32. Tan ZY, Cai S, Noble AJ, Chen JK, Shi J, Gan L. Heterogeneous non-canonical nucleosomes predominate in yeast cells in situ. bioRxiv. 2021:2021.2004.2004.438362. [preprint]
  33. Tarasova E, Dhindwal S, Popp M, Hussain S, Khayat R. Mechanism of DNA Interaction and Translocation by the Replicase of a Circular Rep-Encoding Single-Stranded DNA Virus. mBio. 2021;12(4):e0076321.
  34. Valencia-Sanchez MI, Abini-Agbomson S, Wang M, Lee R, Vasilyev N, Zhang J, De Ioannes P, La Scola B, Talbert P, Henikoff S, Nudler E, Erives A, Armache KJ. The structure of a virus-encoded nucleosome. Nat Struct Mol Biol. 2021.
  35. Xiang X, Arakhamia T, Carlomagno Y, Dhingra S, Thierry M, DeTure M, Cook CN, Dickson DW, Petrucelli L, Fitzpatrick AWP. Role of molecular polymorphism in defining tau filament structures in neurodegenerative diseases. bioRxiv. 2021. [preprint]
  36. Yu Y, Li S, Ser Z, Sanyal T, Choi K, Wan B, Kuang H, Sali A, Kentsis A, Patel DJ, Zhao X. Integrative analysis reveals unique structural and functional features of the Smc5/6 complex. Proc Natl Acad Sci U S A. 2021;118(19).

2020 (47)

  1. Arakhamia T, Lee CE, Carlomagno Y, Duong DM, Kundinger SR, Wang K, Williams D, DeTure M, Dickson DW, Cook CN, Seyfried NT, Petrucelli L, Fitzpatrick AWP. Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains. Cell. 2020;180(4):633-644 e612.
  2. Bepler T, Kelley K, Noble AJ, Berger B. Topaz-Denoise: general deep denoising models for cryoEM and cryoET. Nat Commun. 2020;11(1):5208.
  3. Bhardwaj R, Lindinger S, Neuberger A, Nadezhdin KD, Singh AK, Cunha MR, Derler I, Gyimesi G, Reymond JL, Hediger MA, Romanin C, Sobolevsky AI. Inactivation-mimicking block of the epithelial calcium channel TRPV6. Sci Adv. 2020;6(48).
  4. Carter SD, Hampton CM, Langlois R, Melero R, Farino ZJ, Calderon MJ, Li W, Wallace CT, Tran NH, Grassucci RA, Siegmund SE, Pemberton J, Morgenstern TJ, Eisenman L, Aguilar JI, Greenberg NL, Levy ES, Yi E, Mitchell WG, Rice WJ, Wigge C, Pilli J, George EW, Aslanoglou D, Courel M, Freyberg RJ, Javitch JA, Wills ZP, Area-Gomez E, Shiva S, Bartolini F, Volchuk A, Murray SA, Aridor M, Fish KN, Walter P, Balla T, Fass D, Wolf SG, Watkins SC, Carazo JM, Jensen GJ, Frank J, Freyberg Z. Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells. Sci Adv. 2020;6(14):eaay9572.
  5. Chen J, Malone B, Llewellyn E, Grasso M, Shelton PMM, Olinares PDB, Maruthi K, Eng ET, Vatandaslar H, Chait BT, Kapoor TM, Darst SA, Campbell EA. Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex. Cell. 2020;182(6):1560-1573 e1513.
  6. Coudray N, Isom GL, MacRae MR, Saiduddin MN, Bhabha G, Ekiert DC. Structure of bacterial phospholipid transporter MlaFEDB with substrate bound. Elife. 2020;9.
  7. Dandey VP, Budell WC, Wei H, Bobe D, Maruthi K, Kopylov M, Eng ET, Kahn PA, Hinshaw JE, Kundu N, Nimigean CM, Fan C, Sukomon N, Darst SA, Saecker RM, Chen J, Malone B, Potter CS, Carragher B. Time-resolved cryo-EM using Spotiton. Nat Methods. 2020;17(9):897-900.
  8. Durie CL, Sheedlo MJ, Chung JM, Byrne BG, Su M, Knight T, Swanson M, Lacy DB, Ohi MD. Structural analysis of the Legionella pneumophila Dot/Icm type IV secretion system core complex. Elife. 2020;9.
  9. Fan C, Sukomon N, Flood E, Rheinberger J, Allen TW, Nimigean CM. Ball-and-chain inactivation in a calcium-gated potassium channel. Nature. 2020;580(7802):288-293.
  10. Feaga HA, Kopylov M, Kim JK, Jovanovic M, Dworkin J. Ribosome Dimerization Protects the Small Subunit. J Bacteriol. 2020;202(10).
  11. Ferranti CS, Cheng J, Thompson C, Zhang J, Rotolo JA, Buddaseth S, Fuks Z, Kolesnick RN. Fusion of lysosomes to plasma membrane initiates radiation-induced apoptosis. J Cell Biol. 2020;219(4):e201903177.
  12. Fritzsching KJ, Yang Y, Pogue EM, Rayman JB, Kandel ER, McDermott AE. Micellar TIA1 with folded RNA binding domains as a model for reversible stress granule formation. Proc Natl Acad Sci U S A. 2020;117(50):31832-31837.
  13. Gomez-Llorente Y, Jebara F, Patra M, Malik R, Nisemblat S, Chomsky-Hecht O, Parnas A, Azem A, Hirsch JA, Ubarretxena-Belandia I. Structural basis for active single and double ring complexes in human mitochondrial Hsp60-Hsp10 chaperonin. Nat Commun. 2020;11(1):1916.
  14. Gorman J, Chuang GY, Lai YT, Shen CH, Boyington JC, Druz A, Geng H, Louder MK, McKee K, Rawi R, Verardi R, Yang Y, Zhang B, Doria-Rose NA, Lin B, Moore PL, Morris L, Shapiro L, Mascola JR, Kwong PD. Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition. Cell reports. 2020;31(1):107488.
  15. Halpin-Healy TS, Klompe SE, Sternberg SH, Fernandez IS. Structural basis of DNA targeting by a transposon-encoded CRISPR-Cas system. Nature. 2020;577(7789):271-274.
  16. Harrison OJ, Brasch J, Katsamba PS, Ahlsen G, Noble AJ, Dan H, Sampogna RV, Potter CS, Carragher B, Honig B, Shapiro L. Family-wide Structural and Biophysical Analysis of Binding Interactions among Non-clustered delta-Protocadherins. Cell reports. 2020;30(8):2655-2671 e2657.
  17. Kendall AK, Xie B, Xu P, Wang J, Burcham R, Frazier MN, Binshtein E, Wei H, Graham TR, Nakagawa T, Jackson LP. Mammalian Retromer Is an Adaptable Scaffold for Cargo Sorting from Endosomes. Structure. 2020;28(4):393-405 e394.
  18.  Koripella RK, Deep A, Agrawal EK, Keshavan P, Banavali NK, Agrawal RK. Structures of the human mitochondrial ribosome recycling complexes reveal distinct mechanisms of recycling and antibiotic resistance. bioRxiv. 2020. [preprint]
  19. Koripella RK, Sharma MR, Bhargava K, Datta PP, Kaushal PS, Keshavan P, Spremulli LL, Banavali NK, Agrawal RK. Structures of the human mitochondrial ribosome bound to EF-G1 reveal distinct features of mitochondrial translation elongation. Nat Commun. 2020;11(1):3830.
  20. Kumar P, Wang Y, Zhang Z, Zhao Z, Cymes GD, Tajkhorshid E, Grosman C. Cryo-EM structures of a lipid-sensitive pentameric ligand-gated ion channel embedded in a phosphatidylcholine-only bilayer. Proc Natl Acad Sci U S A. 2020;117(3):1788-1798.
  21. Lilic M, Chen J, Boyaci H, Braffman N, Hubin EA, Herrmann J, Muller R, Mooney R, Landick R, Darst SA, Campbell EA. The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase. Proc Natl Acad Sci U S A. 2020;117(48):30423-30432.
  22. Malik R, Kopylov M, Gomez-Llorente Y, Jain R, Johnson RE, Prakash L, Prakash S, Ubarretxena-Belandia I, Aggarwal AK. Structure and mechanism of B-family DNA polymerase zeta specialized for translesion DNA synthesis. Nat Struct Mol Biol. 2020;27(10):913-924.
  23. Marcink TC, Wang T, des Georges A, Porotto M, Moscona A. Human parainfluenza virus fusion complex glycoproteins imaged in action on authentic viral surfaces. PLoS Pathog. 2020;16(9):e1008883.
  24. Maruthi K, Kopylov M, Carragher B. Automating Decision Making in the Cryo-EM Pre-processing Pipeline. Structure. 2020;28(7):727-729.
  25. Murphy EL, Singh KV, Avila B, Kleffmann T, Gregory ST, Murray BE, Krause KL, Khayat R, Jogl G. Cryo-electron microscopy structure of the 70S ribosome from Enterococcus faecalis. Sci Rep. 2020;10(1):16301.
  26. Neupane R, Pisareva VP, Rodriguez CF, Pisarev AV, Fernandez IS. A complex IRES at the 5′-UTR of a viral mRNA assembles a functional 48S complex via an uAUG intermediate. Elife. 2020;9:e54575.
  27. Owji AP, Zhao Q, Ji C, Kittredge A, Hopiavuori A, Fu Z, Ward N, Clarke OB, Shen Y, Zhang Y, Hendrickson WA, Yang T. Structural and functional characterization of the bestrophin-2 anion channel. Nat Struct Mol Biol. 2020;27(4):382-391.
  28. Park J, Fu Z, Frangaj A, Liu J, Mosyak L, Shen T, Slavkovich VN, Ray KM, Taura J, Cao B, Geng Y, Zuo H, Kou Y, Grassucci R, Chen S, Liu Z, Lin X, Williams JP, Rice WJ, Eng ET, Huang RK, Soni RK, Kloss B, Yu Z, Javitch JA, Hendrickson WA, Slesinger PA, Quick M, Graziano J, Yu H, Fiehn O, Clarke OB, Frank J, Fan QR. Structure of human GABAB receptor in an inactive state. Nature. 2020;584(7820):304-309.
  29. Passos DO, Li M, Jozwik IK, Zhao XZ, Santos-Martins D, Yang R, Smith SJ, Jeon Y, Forli S, Hughes SH, Burke TR, Jr., Craigie R, Lyumkis D. Structural basis for strand-transfer inhibitor binding to HIV intasomes. Science. 2020;367(6479):810-814.
  30. Rapp M, Carragher B. Better, faster, and even cheap. Science. 2020;370(6513):171.
  31. Schmidpeter PAM, Rheinberger J, Nimigean CM. Prolyl isomerization controls activation kinetics of a cyclic nucleotide-gated ion channel. Nat Commun. 2020;11(1):6401.
  32. Schrecker M, Korobenko J, Hite RK. Cryo-EM structure of the lysosomal chloride-proton exchanger CLC-7 in complex with OSTM1. Elife. 2020;9.
  33. Sheedlo MJ, Chung JM, Sawhney N, Durie CL, Cover TL, Ohi MD, Lacy DB. Cryo-EM reveals species-specific components within the Helicobacter pylori Cag type IV secretion system core complex. Elife. 2020;9:e59495.
  34. Su M, Zhu L, Zhang Y, Paknejad N, Dey R, Huang J, Lee MY, Williams D, Jordan KD, Eng ET, Ernst OP, Meyerson JR, Hite RK, Walz T, Liu W, Huang XY. Structural Basis of the Activation of Heterotrimeric Gs-Protein by Isoproterenol-Bound beta1-Adrenergic Receptor. Mol Cell. 2020;80(1):59-71 e54.
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2017 (24)

  1. Alewijnse B, Ashton AW, Chambers MG, Chen S, Cheng A, Ebrahim M, Eng ET, Hagen WJH, Koster AJ, Lopez CS, Lukoyanova N, Ortega J, Renault L, Reyntjens S, Rice WJ, Scapin G, Schrijver R, Siebert A, Stagg SM, Grum-Tokars V, Wright ER, Wu S, Yu Z, Zhou ZH, Carragher B, Potter CS. Best practices for managing large CryoEM facilities.  J Struct Biol. 2017;199(3):225-236.  Pubmed.
  2. Baldwin PR, Tan YZ, Eng ET, Rice WJ, Noble AJ, Negro CJ, Cianfrocco MA, Potter CS, Carragher B.  Big data in cryoEM: automated collection, processing and accessibility of EM data. Curr Opin Microbiol. 2017;43:1-8.  Pubmed.
  3. Benoit MPMH, Asenjo AB, Sosa H.  Cryo-EM Reveals the Structural Basis of Microtubule Depolymerization by Kinesin-13s  DOI.
  4. Chowdhury S, Carter J, Rollins MF, Golden SM, Jackson RN, Hoffmann C, Nosaka L, Bondy-Denomy J, Maxwell KL, Davidson AR, Fischer ER, Lander GC, Wiedenheft B. Structure Reveals Mechanisms of Viral Suppressors that Intercept a CRISPR RNA-Guided Surveillance Complex. Cell. 2017;169(1):47-57 e11.  Pubmed.
  5. Garcia-Marin V, Kelly JG, Hawken MJ.  Major Feedforward Thalamic Input Into Layer 4C of Primary Visual Cortex in Primate.  Cereb Cortex. 2017;1-16. Pubmed.
  6. Geary C, Chworos A, Verzemnieks E, Voss NR, Jaeger L.  Composing RNA Nanostructures from a Syntax of RNA Structural Modules. Nano Lett. 2017;17(11): 7095-7101.  Pubmed.
  7. Guo H, Bueler SA, Rubinstein JL.  Atomic model for the dimeric FO region of mitochondrial ATP synthase. Science. 2017;358(6365):936-940.  Pubmed.
  8. Guo TW, Bartesaghi A, Yang H, Falconieri V, Rao P, Merk A, Eng ET, Raczkowski AM, Fox T, Earl LA, Patel DJ, Subramaniam S.  Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. Cell. 2017;171(2): 414-426 e12.  Pubmed.
  9. Hamachi LS, Jen-La Plante I, Coryell AC, De Roo J, Owen JS.  Kinetic Control over CdS Nanocrystal Nucleation Using a Library of Thiocarbonates, Thiocarbamates, and Thioureas.  Chemistry of Materials. 2017;29(20):8711-8719. DOI.
  10. Han H, Monroe N, Sundquist WI, Shen PS, Hill, CP.  The AAA ATPase Vps4 binds ESCRT-III substrates through a repeating array of dipeptide-binding pockets. Elife. 2017;6.  Pubmed.
  11. James ZM, Borst AJ, Haitin Y, Frenz B, DiMaio F, Zagotta WN, Veesler D.  CryoEM structure of a prokaryotic cyclic nucleotide-gated ion channel.  Proc Natl Acad Sci U S A. 2017;114(17):4430-4435. Pubmed.
  12. Kulczyk AW, Moeller A, Meyer P, Sliz P, Richardson CC.  Cryo-EM structure of the replisome reveals multiple interactions coordinating DNA synthesis.  Proc Natl Acad Sci U S A. 2017;114(10):E1848-E1856. PMCID: PMC5347612. Pubmed.
  13. Lin W, Das K, Degen D, Mazumder A, Duchi D, Wang D, Ebright YW, Ebright RY, Sineva E, Gigliotti M, Srivastava A, Mandal S, Jiang Y, Liu Y, Yin R, Zhang Z, Eng E, Thomas D, Donadio S, Zhang H, Zhang C, Kapanidis A, Ebright RH. Structural basis of transcription inhibition by fidaxomicin (lipiarmycin A3). bioRxiv 2017. DOI.
  14. Liu Q, Acharya P, Dolan MA, Zhang P, Guzzo C, Lu J, Kwon A, Gururani D, Miao H, Bylund T, Chuang GY, Druz A, Zhou T, Rice WJ, Wigge C, Carragher B, Potter CS, Kwong PD, Lusso P.  Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer. Nat Struct Mol Biol. 2017;24(4):370-378. Pubmed.
  15. Noble AJ, Dandey VP, Wei H, Brasch J, Chase J, Acharya P, Tan YZ, Zhang Z, Kim LY, Scapin G, Rapp M, Eng ET, Rice WJ, Cheng A, Negro CJ, Shapiro L, Kwong PD, Jeruzalmi D, des Georges A, Potter CS, Carragher B.  Routine Single Particle CryoEM Sample and Grid Characterization by Tomography. bioRxiv 2017 DOI.
  16. Pentakota S, Zhou K, Smith C, Maffini S, Petrovic A, Morgan G, Weir JR, Vetter IR, Musacchio A, Luger K.   Decoding the centromeric nucleosome through CENP-N.  eLife. 2017;6:e33442.  DOI.
  17. Piasecka A, Czapinska H, Vielberg MT, Szczepanowski R, Kiefersauer R, Reed S, Groll M, Bochtler M.  The Y. bercovieri Anbu crystal structure sheds light on the evolution of highly (pseudo)symmetric multimers.  J Mol Biol. 2017.  Pubmed.
  18. Scapin G, Prosise WW, Wismer MK, Strickland C.  A novel storage system for cryoEM samples.  J Struct Biol. 2017;199(1):84-86.  Pubmed.
  19. Sherman MB, Kakani K., Rochon D, Jiang W, Voss NR, Smith TJ.  Stability of Cucumber Necrosis Virus at the Quasi-6-Fold Axis Affects Zoospore Transmission. J Virol.  2017;91(19).  Pubmed.
  20. Tan YZ, Baldwin PR, Davis JH, Williamson JR, Potter CS, Carragher B, Lyumkis D.  Addressing preferred specimen orientation in single-particle cryo-EM through tilting. Nature Methods. 2017;14(8):793-796.  Pubmed.
  21. Twomey EC, Yelshanskaya MV, Grassucci RA, Frank J, Sobolevsky AI.  Channel opening and gating mechanism in AMPA-subtype glutamate receptors.  Nature. 2017;549(7670): 60-65. Pubmed.
  22. Yang H, Jiang X, Li B, Yang HJ, Miller M, Yang A, Dhar A, Pavletich NP.  Mechanisms of mTORC1 activation by RHEB and inhibition by PRAS40.  Nature. 2017;552(7685):368-373. Pubmed.
  23. Yu X, Veesler D, Campbell MG, Barry ME, Asturias FJ, Barry MA, Reddy VS.  Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses.  Sci Adv. 2017;3(5):e1602670. PMCID: PMC5425241. Pubmed.
  24. Yuan Z, Riera A, Bai L, Sun J, Nandi S, Spanos C, Chen ZA, Barbon M, Rappsilber J, Stillman B, Speck C, Li H.  Structural basis of Mcm2-7 replicative helicase loading by ORC-Cdc6 and Cdt1.  Nat Struct Mol Biol. 2017;24(3):316-324. Pubmed.

2016 (13)

  1. Ballandras-Colas A, Brown M, Cook NJ, Dewdney TG, Demeler B, Cherepanov P, Lyumkis D, Engelman AN. Cryo-EM reveals a novel octameric integrase structure for betaretroviral intasome function. Nature. 2016;530(7590):358-61. PMCID: 4908968. Pubmed.
  2. Cheng A, Tan YZ, Dandey VP, Potter CS, Carragher B.  Strategies for Automated CryoEM Data Collection Using Direct Detectors. Methods Enzymol 2016;579:87-102. Pubmed.
  3. Davis JH, Tan YZ, Carragher B, Potter CS, Lyumkis D, Williamson JR. Modular Assembly of the Bacterial Large Ribosomal Subunit. Cell 2016;167(6):1610-1622 e15. Pubmed.
  4. Gui L, Ebner JL, Mileant A, Williams JA, Lee KK. Visualization and sequencing of Membrane Remodeling Leading to Influenza Virus Fusion. J Virol. 2016;90(15):6948-62 PMCID: In Process. Pubmed.
  5. Kuruganti S, Miersch S, Deshpande A, Speir JA, Harris BD, Schriewer JM, Buller RM, Sidhu SS, Walter MR. Cytokine Activation by Antibody Fragments Targeted to Cytokine-Receptor Signaling Complexes. J Biol Chem. 2016;291(1):447-61. PMCID: 4697184. Pubmed
  6. Razinkov I, Dandey VP, Wei H, Zhang Z, Melnekoff D, Rice WJ, Wigge C, Potter CS, Carragher B. A new method for vitrifying samples for cryoEM. J Struct Biol. 2016;195(2):190-198.  PMCID: In Process. Pubmed
  7. Severin C, Terrell JR, Zengel JR, Cox R, Plemper RK, He B, Luo M.  Releasing the genomic RNA sequestered in the mumps virus nucleocapsid. J Virol. 2016; Pubmed
  8. Short JR, Speir JA, Gopal R, Pankratz LM, Lanman J, Schneemann A. Role of Mitochondrial Membrane Spherules in Flock House Virus Replication. J Virol. 2016;90(7):3676-83. PMCID: 4794695. Pubmed
  9. Tan YZ, Cheng A, Potter CS, Carragher B. Automated data collection in single particle electron microscopy. Microscopy (Oxf). 2016;65(1):43-56. PMCID: 4749047. Pubmed
  10. Verba KA, Wang RY, Arakawa A, Liu Y, Shirouzu M, Yokoyama S, Agard DA. Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase. Science. 2016;352(6293):1542-7. PMCID: In Process.  Pubmed
  11. Walls AC, Tortorici MA, Bosch BJ, Frenz B, Rottier PJ, DiMaio F, Rey FA, Veesler D. Cryo-electron microscopy structure of a coronavirus spike glycoprotein trimer. Nature. 2016;531(7592):114-7. PMCID: 4749047. Pubmed
  12. Yap ML, Klose T, Arisaka F, Speir JA, Veesler D, Fokine A, Rossmann MG. Role of bacteriophage T4 baseplate in regulating assembly and infection. Proc Natl Acad Sci U S A. 2016;113(10):2654-9. PMCID: 4791028. Pubmed
  13. Zhao H, Speir JA, Matsui T, Lin Z, Liang L, Lynn AY, Varnado B, Weiss TM, Tang L. Structure of a Bacterial Virus DNA-Injection Protein Complex Reveals a Decameric Assembly with a Constricted Molecular Channel. PLoS One. 2016;11(2):e0149337. PMCID: 4755594.  Pubmed

2015 (21)

  1. Campbell MG, Veesler D, Cheng A, Potter CS, Carragher B. 2.8 A resolution reconstruction of the Thermoplasma acidophilum 20S proteasome using cryo-electron microscopy. Elife. 2015;4. PMCID: 4391500. Pubmed
  2. Carragher B, Potter CS. Recent advances in new technologies and applications for molecular TEM. J Struct Biol. 2015;192(2):145. Not Peer Reviewed. Pubmed
  3. Cheng A, Henderson R, Mastronarde D, Ludtke SJ, Schoenmakers RH, Short J, Marabini R, Dallakyan S, Agard D, Winn M. MRC2014: Extensions to the MRC format header for electron cryo-microscopy and tomography. J Struct Biol. 2015;192(2):146-50. PMCID: 4642651. Pubmed
  4. Derking R, Ozorowski G, Sliepen K, Yasmeen A, Cupo A, Torres JL, Julien JP, Lee JH, van Montfort T, de Taeye SW, Connors M, Burton DR, Wilson IA, Klasse PJ, Ward AB, Moore JP, Sanders RW. Comprehensive Antigenic Map of a Cleaved Soluble HIV-1 Envelope Trimer. PLoS Pathog. 2015;11(3):e1004767. PMCID: 4373910. Pubmed
  5. Flyak AI, Ilinykh PA, Murin CD, Garron T, Shen X, Fusco ML, Hashiguchi T, Bornholdt ZA, Slaughter JC, Sapparapu G, Klages C, Ksiazek TG, Ward AB, Saphire EO, Bukreyev A, Crowe JE, Jr. Mechanism of human antibody-mediated neutralization of Marburg virus. Cell. 2015;160(5):893-903. PMCID: 4344968. Pubmed
  6. Garnham CP, Vemu A, Wilson-Kubalek EM, Yu I, Szyk A, Lander GC, Milligan RA, Roll-Mecak A. Multivalent Microtubule Recognition by Tubulin Tyrosine Ligase-like Family Glutamylases. Cell. 2015;161(5):1112-23. PMCID: 4465277. Pubmed
  7. Grant T, Grigorieff N. Measuring the optimal exposure for single particle cryo-EM using a 2.6 A reconstruction of rotavirus VP6. Elife. 2015;4:e06980. PMCID: 4471936. Pubmed
  8. Guenaga J, de Val N, Tran K, Feng Y, Satchwell K, Ward AB, Wyatt RT. Well-ordered trimeric HIV-1 subtype B and C soluble spike mimetics generated by negative selection display native-like properties. PLoS Pathog. 2015;11(1):e1004570. PMCID: 4287557. Pubmed
  9. Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, Chapman HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE. Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser. Nature. 2015;523(7562):561-7. PMCID: 4521999. Pubmed
  10. Lee JH, Leaman DP, Kim AS, Torrents de la Pena A, Sliepen K, Yasmeen A, Derking R, Ramos A, de Taeye SW, Ozorowski G, Klein F, Burton DR, Nussenzweig MC, Poignard P, Moore JP, Klasse PJ, Sanders RW, Zwick MB, Wilson IA, Ward AB. Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike. Nat Commun. 2015;6:8167. PMCID: 4586043. Pubmed
  11. Leung JH, Schurig-Briccio LA, Yamaguchi M, Moeller A, Speir JA, Gennis RB, Stout CD. Structural biology. Division of labor in transhydrogenase by alternating proton translocation and hydride transfer. Science. 2015;347(6218):178-81. PMCID: 4479213. Pubmed
  12. Majzoub RN, Ewert KK, Jacovetty EL, Carragher B, Potter CS, Li Y, Safinya CR. Patterned Threadlike Micelles and DNA-Tethered Nanoparticles: A Structural Study of PEGylated Cationic Liposome-DNA Assemblies. Langmuir. 2015;31(25):7073-83. PMCID: 4554524. Pubmed
  13. Marabini R, Carragher B, Chen S, Chen J, Cheng A, Downing KH, Frank J, Grassucci RA, Bernard Heymann J, Jiang W, Jonic S, Liao HY, Ludtke SJ, Patwari S, Piotrowski AL, Quintana A, Sorzano CO, Stahlberg H, Vargas J, Voss NR, Chiu W, Carazo JM. CTF Challenge: Result summary. J Struct Biol. 2015;190(3):348-59. PMCID: 4672951. Pubmed
  14. McCullough J, Clippinger AK, Talledge N, Skowyra ML, Saunders MG, Naismith TV, Colf LA, Afonine P, Arthur C, Sundquist WI, Hanson PI, Frost A. Structure and membrane remodeling activity of ESCRT-III helical polymers. Science. 2015;350(6267):1548-51. PMCID: 4684769. Pubmed
  15. McNulty R, Lokareddy RK, Roy A, Yang Y, Lander GC, Heck AJ, Johnson JE, Cingolani G. Architecture of the Complex Formed by Large and Small Terminase Subunits from Bacteriophage P22. J Mol Biol. 2015;427(20):3285-99. PMCID: 4587339. Pubmed
  16. Moeller A, Lee SC, Tao H, Speir JA, Chang G, Urbatsch IL, Potter CS, Carragher B, Zhang Q. Distinct conformational spectrum of homologous multidrug ABC transporters. Structure. 2015;23(3):450-60. PMCID: 4351144. Pubmed
  17. Mulligan SK, Speir JA, Razinkov I, Cheng A, Crum J, Jain T, Duggan E, Liu E, Nolan JP, Carragher B, Potter CS. Multiplexed TEM Specimen Preparation and Analysis of Plasmonic Nanoparticles. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 2015;21(4):1017-25. PMCID: 4701052. Pubmed
  18. Pugach P, Ozorowski G, Cupo A, Ringe R, Yasmeen A, de Val N, Derking R, Kim HJ, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, Julien JP, Burton DR, Wilson IA, Sanders RW, Klasse PJ, Ward AB, Moore JP. A native-like SOSIP.664 trimer based on an HIV-1 subtype B env gene. J Virol. 2015;89(6):3380-95. PMCID: 4337520. Pubmed
  19. Sheth LK, Piotrowski AL, Voss NR. Visualization and quality assessment of the contrast transfer function estimation. J Struct Biol. 2015;192(2):222-34. PMCID: In process. Pubmed
  20. Yang L, Yang D, de Graaf C, Moeller A, West GM, Dharmarajan V, Wang C, Siu FY, Song G, Reedtz-Runge S, Pascal BD, Wu B, Potter CS, Zhou H, Griffin PR, Carragher B, Yang H, Wang MW, Stevens RC, Jiang H. Conformational states of the full-length glucagon receptor. Nat Commun. 2015;6:7859. PMCID: 4532856. Pubmed
  21. Ye Q, Rosenberg SC, Moeller A, Speir JA, Su TY, Corbett KD. TRIP13 is a protein-remodeling AAA+ ATPase that catalyzes MAD2 conformation switching. Elife. 2015;4. PMCID: 4439613. Pubmed

2014 (23)

  1. Bhabha G, Cheng HC, Zhang N, Moeller A, Liao M, Speir JA, Cheng Y, Vale RD. Allosteric communication in the Dynein motor domain. Cell. 2014;159(4):857-68. PMCID: 4269335. Pubmed
  2. Blattner C, Lee JH, Sliepen K, Derking R, Falkowska E, de la Pena AT, Cupo A, Julien JP, van Gils M, Lee PS, Peng W, Paulson JC, Poignard P, Burton DR, Moore JP, Sanders RW, Wilson IA, Ward AB. Structural delineation of a quaternary, cleavage-dependent epitope at the gp41-gp120 interface on intact HIV-1 Env trimers. Immunity. 2014;40(5):669-80. PMCID: 4057017. Pubmed
  3. Butan C, Filman DJ, Hogle JM. Cryo-electron microscopy reconstruction shows poliovirus 135S particles poised for membrane interaction and RNA release. J Virol. 2014;88(3):1758-70. PMCID: 3911577. Pubmed
  4. Campbell MG, Kearney BM, Cheng A, Potter CS, Johnson JE, Carragher B, Veesler D. Near-atomic resolution reconstructions using a mid-range electron microscope operated at 200 kV. J Struct Biol. 2014;188(2):183-7. PMCID: 4497823. Pubmed
  5. Campbell MG, Smith BC, Potter CS, Carragher B, Marletta MA. Molecular architecture of mammalian nitric oxide synthases. Proc Natl Acad Sci U S A. 2014;111(35):E3614-23. PMCID: 4156747. Pubmed
  6. Campbell MG, Underbakke ES, Potter CS, Carragher B, Marletta MA. Single-particle EM reveals the higher-order domain architecture of soluble guanylate cyclase. Proc Natl Acad Sci U S A. 2014;111(8):2960-5. PMCID: 3939929. Pubmed
  7. Friesen RH, Lee PS, Stoop EJ, Hoffman RM, Ekiert DC, Bhabha G, Yu W, Juraszek J, Koudstaal W, Jongeneelen M, Korse HJ, Ophorst C, Brinkman-van der Linden EC, Throsby M, Kwakkenbos MJ, Bakker AQ, Beaumont T, Spits H, Kwaks T, Vogels R, Ward AB, Goudsmit J, Wilson IA. A common solution to group 2 influenza virus neutralization. Proc Natl Acad Sci U S A. 2014;111(1):445-50. PMCID: 3890827. Pubmed
  8. Garces F, Sok D, Kong L, McBride R, Kim HJ, Saye-Francisco KF, Julien JP, Hua Y, Cupo A, Moore JP, Paulson JC, Ward AB, Burton DR, Wilson IA. Structural evolution of glycan recognition by a family of potent HIV antibodies. Cell. 2014;159(1):69-79. PMCID: 4278586. Pubmed
  9. Grover RK, Zhu X, Nieusma T, Jones T, Boero I, MacLeod AS, Mark A, Niessen S, Kim HJ, Kong L, Assad-Garcia N, Kwon K, Chesi M, Smider VV, Salomon DR, Jelinek DF, Kyle RA, Pyles RB, Glass JI, Ward AB, Wilson IA, Lerner RA. A structurally distinct human mycoplasma protein that generically blocks antigen-antibody union. Science. 2014;343(6171):656-61. PMCID: 3987992. Pubmed
  10. Hsia KC, Wilson-Kubalek EM, Dottore A, Hao Q, Tsai KL, Forth S, Shimamoto Y, Milligan RA, Kapoor TM. Reconstitution of the augmin complex provides insights into its architecture and function. Nat Cell Biol. 2014;16(9):852-63. PMCID: 4244909. Pubmed
  11. Liu T, Sae-Ueng U, Li D, Lander GC, Zuo X, Jonsson B, Rau D, Shefer I, Evilevitch A. Solid-to-fluid-like DNA transition in viruses facilitates infection. Proc Natl Acad Sci U S A. 2014;111(41):14675-80. PMCID: 4205597. Pubmed
  12. Lyumkis D, Oliveira dos Passos D, Tahara EB, Webb K, Bennett EJ, Vinterbo S, Potter CS, Carragher B, Joazeiro CA. Structural basis for translational surveillance by the large ribosomal subunit-associated protein quality control complex. Proc Natl Acad Sci U S A. 2014;11(45):15981-6. PMCID: 4234556. Pubmed
  13. Majzoub RN, Chan CL, Ewert KK, Silva BF, Liang KS, Jacovetty EL, Carragher B, Potter CS, Safinya CR. Uptake and transfection efficiency of PEGylated cationic liposome-DNA complexes with and without RGD-tagging. Biomaterials. 2014;35(18):4996-5005. PMCID: 4032065. Pubmed
  14. Matho MH, de Val N, Miller GM, Brown J, Schlossman A, Meng X, Crotty S, Peters B, Xiang Y, Hsieh-Wilson LC, Ward AB, Zajonc DM. Murine anti-vaccinia virus D8 antibodies target different epitopes and differ in their ability to block D8 binding to CS-E. PLoS Pathog. 2014;10(12):e1004495. PMCID: 4256255. Pubmed
  15. Murin CD, Fusco ML, Bornholdt ZA, Qiu X, Olinger GG, Zeitlin L, Kobinger GP, Ward AB, Saphire EO. Structures of protective antibodies reveal sites of vulnerability on Ebola virus. Proc Natl Acad Sci U S A. 2014;111(48):17182-7. PMCID: 4260551. Pubmed
  16. Murin CD, Julien JP, Sok D, Stanfield RL, Khayat R, Cupo A, Moore JP, Burton DR, Wilson IA, Ward AB. Structure of 2G12 Fab2 in complex with soluble and fully glycosylated HIV-1 Env by negative-stain single-particle electron microscopy. J Virol. 2014;88(17):10177-88. PMCID: 4136306. Pubmed
  17. Nolan JP, Duggan E, Condello D. Optimization of SERS tag intensity, binding footprint, and emittance. Bioconjug Chem. 2014;25(7):1233-42. PMCID: 4215889. Pubmed
  18. Parent KN, Erb ML, Cardone G, Nguyen K, Gilcrease EB, Porcek NB, Pogliano J, Baker TS, Casjens SR. OmpA and OmpC are critical host factors for bacteriophage Sf6 entry in Shigella. Mol Microbiol. 2014;92(1):47-60. PMCID: 4034267. Pubmed
  19. Pratt AJ, Shin DS, Merz GE, Rambo RP, Lancaster WA, Dyer KN, Borbat PP, Poole FL, 2nd, Adams MW, Freed JH, Crane BR, Tainer JA, Getzoff ED. Aggregation propensities of superoxide dismutase G93 hotspot mutants mirror ALS clinical phenotypes. Proc Natl Acad Sci U S A. 2014;111(43):E4568-76. PMCID: 4217430. Pubmed
  20. Sashital DG, Greeman CA, Lyumkis D, Potter CS, Carragher B, Williamson JR. A combined quantitative mass spectrometry and electron microscopy analysis of ribosomal 30S subunit assembly in E. coli. Elife. 2014;3. PMCID: 4371863. Pubmed
  21. Scharf L, Scheid JF, Lee JH, West AP, Jr., Chen C, Gao H, Gnanapragasam PN, Mares R, Seaman MS, Ward AB, Nussenzweig MC, Bjorkman PJ. Antibody 8ANC195 reveals a site of broad vulnerability on the HIV-1 envelope spike. Cell Rep. 2014;7(3):785-95. PMCID: 4109818. Pubmed
  22. Veesler D, Cupelli K, Burger M, Graber P, Stehle T, Johnson JE. Single-particle EM reveals plasticity of interactions between the adenovirus penton base and integrin alphaVbeta3. Proc Natl Acad Sci U S A. 2014;111(24):8815-9. PMCID: 4066496. Pubmed
  23. Veesler D, Khayat R, Krishnamurthy S, Snijder J, Huang RK, Heck AJ, Anand GS, Johnson JE. Architecture of a dsDNA viral capsid in complex with its maturation protease. Structure. 2014;22(2):230-7. PMCID: 3939775. Pubmed

2013 (32)

1. Cheng A. Automation of data acquisition in electron crystallography. Methods Mol Biol. 2013;955:307-12. PMCID Not Peered Reviewed. PubMed
2. Cheng A. Automated grid handling and image acquisition for two-dimensional crystal screening. Methods Mol Biol. 2013;955:297-305. PMCID Not Peered Reviewed. PubMed
3. Cui H, Mim C, Vazquez FX, Lyman E, Unger VM, Voth GA. Understanding the Role of Amphipathic Helices in N-BAR Domain Driven Membrane Remodeling. Biophys J. 2013;104(2):404-11. PMCID PMC3552260. PubMed
4. Gogol EP, Akkaladevi N, Szerszen L, Mukherjee S, Chollet-Hinton L, Katayama H, Pentelute BL, Collier RJ, Fisher MT. Three dimensional structure of the anthrax toxin translocon-lethal factor complex by cryo-electron microscopy. Protein Sci. 2013;22(5):586-94. PMCID PMC3649260. PubMed
5. Hong M, Lee PS, Hoffman RM, Zhu X, Krause JC, Laursen NS, Yoon SI, Song L, Tussey L, Crowe JE Jr., Ward AB, Wilson IA. Antibody recognition of the pandemic H1N1 Influenza virus hemagglutinin receptor binding site. J Virol. 2013;87(22):12471-80. PMCID PMC3807900. PubMed
6. Julien JP, Cupo A, Sok D, Stanfield RL, Lyumkis D, Deller MC, Klasse PJ, Burton DR, Sanders RW, Moore JP, Ward AB, Wilson IA. Crystal structure of a soluble cleaved HIV-1 envelope trimer. Science. 2013;342(6165):1477-83. PubMed
7. Julien JP, Lee JH, Cupo A, Murin CD, Derking R, Hoffenberg S, Caulfield MJ, King CR, Marozsan AJ, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB. Asymmetric recognition of the HIV-1 trimer by broadly neutralizing antibody PG9. Proc Natl Acad Sci U S A. 2013;110(11):4351-6. PMCID PMC3600498. PubMed
8. Julien JP, Sok D, Khayat R, Lee JH, Doores KJ, Walker LM, Ramos A, Diwanji DC, Pejchal R, Cupo A, Katpally U, Depetris RS, Stanfield RL, McBride R, Marozsan AJ, Paulson JC, Sanders RW, Moore JP, Burton DR, Poignard P, Ward AB, Wilson IA. Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans. PLoS Pathog. 2013;9(5):e1003342. PMCID PMC3642082. PubMed
9. Khayat R, Lee JH, Julien JP, Cupo A, Klasse PJ, Sanders RW, Moore JP, Wilson IA, Ward AB. Structural characterization of cleaved, soluble human immunodeficiency virus type-1 envelope glycoprotein trimers. J Virol. 2013. PMCID PMC3754114 [Available on 2014/3/1]. PubMed
10. Klasse PJ, Depetris RS, Pejchal R, Julien JP, Khayat R, Lee JH, Marozsan AJ, Cupo A, Cocco N, Korzun J, Yasmeen A, Ward AB, Wilson IA, Sanders RW, Moore JP. Influences on Trimerization and Aggregation of Soluble, Cleaved HIV-1 SOSIP Envelope Glycoprotein. J Virol. 2013;87(17):9873-85. PMCID PMC3754145. PubMed
11. Kong L, Giang E, Nieusma T, Kadam RU, Cogburn KE, Hua Y, Dai X, Stanfield RL, Burton DR, Ward AB, Wilson IA, Law M. Hepatitis C virus E2 envelope glycoprotein core structure. Science 2013;342(6162):1090-4. PubMed
12. Kong L, Lee JH, Doores KJ, Murin CD, Julien JP, McBride R, Liu Y, Marozsan A, Cupo A, Klasse PJ, Hoffenberg S, Caulfield M, King CR, Hua Y, Le KM, Khayat R, Deller MC, Clayton T, Tien H, Feizi T, Sanders RW, Paulson JC, Moore JP, Stanfield RL, Burton DR, Ward AB, Wilson IA. Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120. Nat Struct Mol Biol. 2013;20(7):796-803. PMCID PMC3823233. PubMed
13. Lander GC, Johnson JE, Rau DC, Potter CS, Carragher B, Evilevitch A. DNA bending-induced phase transition of encapsidated genome in phage lambda. Nucleic Acids Res. 2013;41(8):4518-24. PMCID PMC3632124. PubMed
14. Lyumkis D, Brilot AF, Theobald DL, Grigorieff N. Likelihood-based classification of cryo-EM images using FREALIGN. J Struct Biol. 2013;183(3):377-88. PMCID PMC3824613. PubMed
15. Lyumkis D, Doamekpor SK, Bengtson MH, Lee JW, Toro TB, Petroski MD, Lima CD, Potter CS, Carragher B, Joazeiro CA. Single-particle EM reveals extensive conformational variability of the Ltn1 E3 ligase. Proc Natl Acad Sci U S A. 2013;110(5):1702-7. PMCID PMC3562785. PubMed
16. Lyumkis D, Julien JP, de Val N, Cupo A, Potter CS, Klasse PJ, Burton DR, Sanders RW, Moore JP, Carragher B, Wilson IA, Ward AB. Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer. Science. 2013;342(6165):1484-90. PubMed
17. Lyumkis D, Talley H, Stewart A, Shah S, Park Chad K, Tama F, Potter Clinton S, Carragher B, Horton Nancy C. Allosteric Regulation of DNA Cleavage and Sequence-Specificity through Run-On Oligomerization. Structure (London, England : 1993). 2013. PubMed
18. Lyumkis D, Vinterbo S, Potter CS, Carragher B. Optimod – An automated approach for constructing and optimizing initial models for single-particle electron microscopy. J Struct Biol. 2013;184(3):417-26. PubMed
19. Minnihan EC, Ando N, Brignole EJ, Olshansky L, Chittuluru J, Asturias FJ, Drennan CL, Nocera DG, Stubbe J. Generation of a stable, aminotyrosyl radical-induced alpha2beta2 complex of Escherichia coli class Ia ribonucleotide reductase. Proc Natl Acad Sci U S A. 2013;110(10):3835-40. PMCID PMC3593893. PubMed
20. Ringe RP, Sanders RW, Yasmeen A, Kim HJ, Lee JH, Cupo A, Korzun J, Derking R, van Montfort T, Julien JP, Wilson IA, Klasse PJ, Ward AB, Moore JP. Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation. Proc Natl Acad Sci U S A. 2013;110(45):18256-61. PMCID PMC3831437. PubMed
21. Ruskin RS, Yu Z, Grigorieff N. Quantitative characterization of electron detectors for transmission electron microscopy. J Struct Biol. 2013;184(3):385-93. PMCID PMC3876735. PubMed
22. Sanders RW, Derking R, Cupo A, Julien JP, Yasmeen A, de Val N, Kim HJ, Blattner C, de la Pena AT, Korzun J, Golabek M, de Los Reyes K, Ketas TJ, van Gils MJ, King CR, Wilson IA, Ward AB, Klasse PJ, Moore JP. A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies. PLoS Pathog. 2013;9(9):e1003618. PMCID PMC3777863. PubMed
23. Shigematsu H, Sigworth FJ. Noise models and cryo-EM drift correction with a direct-electron camera. Ultramicroscopy. 2013;131:61-9. PMCID PMC3736808. PubMed
24. Shin JB, Krey JF, Hassan A, Metlagel Z, Tauscher AN, Pagana JM, Sherman NE, Jeffery ED, Spinelli KJ, Zhao H, Wilmarth PA, Choi D, David LL, Auer M, Barr-Gillespie PG. Molecular architecture of the chick vestibular hair bundle. Nat Neurosci. 2013;16(3):365-74. PMCID PMC3581746. PubMed
25. Tao H, Lee SC, Moeller A, Roy RS, Siu FY, Zimmermann J, Stevens RC, Potter CS, Carragher B, Zhang Q. Engineered nanostructured [beta]-sheet peptides protect membrane proteins. Nat Meth. 2013;10(8):759-61. PMCID PMC3753066. PubMed
26. Thornburg NJ, Nannemann DP, Blum DL, Belser JA, Tumpey TM, Deshpande S, Fritz GA, Sapparapu G, Krause JC, Lee JH, Ward AB, Lee DE, Li S, Winarski KL, Spiller BW, Meiler J, Crowe JE, Jr. Human antibodies that neutralize respiratory droplet transmissible H5N1 influenza viruses. J Clin Invest. 2013;123(10):4405-9. PMCID PMC3784541. PubMed
27. Tsai KL, Sato S, Tomomori-Sato C, Conaway RC, Conaway JW, Asturias FJ. A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction. Nat Struct Mol Biol. 2013;20(5):611-9. PMCID PMC3648612. PubMed
28. Veesler D, Campbell MG, Cheng A, Fu CY, Murez Z, Johnson JE, Potter CS, Carragher B. Maximizing the potential of electron cryomicroscopy data collected using direct detectors. J Struct Biol. 2013;184(2):193-202. PMCID PMC3832241. PubMed
29. Veesler D, Khayat R, Krishnamurthy S, Snijder J, Huang RK, Heck AJ, Anand GS, Johnson JE. Architecture of a dsDNA Viral Capsid in Complex with Its Maturation Protease. Structure. 2013. PubMed
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2012 (26)

1. Aye Y, Brignole EJ, Long MJ, Chittuluru J, Drennan CL, Asturias FJ, Stubbe J. Clofarabine targets the large subunit (alpha) of human ribonucleotide reductase in live cells by assembly into persistent hexamers. Chem Biol. 2012;19(7):799-805. PMCID PMC3408589. PubMed
2. Baudoux AC, Hendrix RW, Lander GC, Bailly X, Podell S, Paillard C, Johnson JE, Potter CS, Carragher B, Azam F. Genomic and functional analysis of Vibrio phage SIO-2 reveals novel insights into ecology and evolution of marine siphoviruses. Environ Microbiol. 2012;14(8):2071-86. PMCID PMC3338904. PubMed
3. Brilot AF, Chen JZ, Cheng A, Pan J, Harrison SC, Potter CS, Carragher B, Henderson R, Grigorieff N. Beam-induced motion of vitrified specimen on holey carbon film. J Struct Biol. 2012;177(3):630-7. PMCID PMC3322646. PubMed
4. Campbell MG, Cheng A, Brilot AF, Moeller A, Lyumkis D, Veesler D, Pan J, Harrison SC, Potter CS, Carragher B, Grigorieff N. Movies of ice-embedded particles enhance resolution in electron cryo-microscopy. Structure. 2012;20(11):1823-8. PMCID PMC3510009. PubMed
5. Clare DK, Vasishtan D, Stagg S, Quispe J, Farr GW, Topf M, Horwich AL, Saibil HR. ATP-triggered conformational changes delineate substrate-binding and -folding mechanics of the GroEL chaperonin. Cell. 2012;149(1):113-23. PMCID PMC3326522. PubMed
6. Depetris RS, Julien JP, Khayat R, Lee JH, Pejchal R, Katpally U, Cocco N, Kachare M, Massi E, David KB, Cupo A, Marozsan AJ, Olson WC, Ward AB, Wilson IA, Sanders RW, Moore JP. Partial enzymatic deglycosylation preserves the structure of cleaved recombinant HIV-1 envelope glycoprotein trimers. J Biol Chem. 2012;287(29):24239-54. PMCID PMC3397850. PubMed
7. Dreyfus C, Laursen NS, Kwaks T, Zuijdgeest D, Khayat R, Ekiert DC, Lee JH, Metlagel Z, Bujny MV, Jongeneelen M, van der Vlugt R, Lamrani M, Korse HJ, Geelen E, Sahin O, Sieuwerts M, Brakenhoff JP, Vogels R, Li OT, Poon LL, Peiris M, Koudstaal W, Ward AB, Wilson IA, Goudsmit J, Friesen RH. Highly conserved protective epitopes on influenza B viruses. Science. 2012;337(6100):1343-8. PMCID PMC3538841. PubMed
8. Ekiert DC, Kashyap AK, Steel J, Rubrum A, Bhabha G, Khayat R, Lee JH, Dillon MA, O’Neil RE, Faynboym AM, Horowitz M, Horowitz L, Ward AB, Palese P, Webby R, Lerner RA, Bhatt RR, Wilson IA. Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature. 2012;489(7417):526-32. PMCID PMC3538848. PubMed
9. Fiedler JD, Higginson C, Hovlid ML, Kislukhin AA, Castillejos A, Manzenrieder F, Campbell MG, Voss NR, Potter CS, Carragher B, Finn MG. Engineered mutations change the structure and stability of a virus-like particle. Biomacromolecules. 2012;13(8):2339-48. PMCID PMC3432585. PubMed
10. Gibbons BJ, Brignole EJ, Azubel M, Murakami K, Voss NR, Bushnell DA, Asturias FJ, Kornberg RD. Subunit architecture of general transcription factor TFIIH. Proc Natl Acad Sci U S A. 2012;109(6):1949-54. PMCID PMC3277522. PubMed
11. Jain T, Sheehan P, Crum J, Carragher B, Potter CS. Spotiton: a prototype for an integrated inkjet dispense and vitrification system for cryo-TEM. J Struct Biol. 2012;179(1):68-75. PMCID PMC3378829. PubMed
12. Lander GC, Baudoux AC, Azam F, Potter CS, Carragher B, Johnson JE. Capsomer dynamics and stabilization in the T = 12 marine bacteriophage SIO-2 and its procapsid studied by CryoEM. Structure. 2012;20(3):498-503. PMCID PMC3302160. PubMed
13. Lander GC, Estrin E, Matyskiela ME, Bashore C, Nogales E, Martin A. Complete subunit architecture of the proteasome regulatory particle. Nature. 2012;482(7384):186-91. PMCID PMC3285539. PubMed
14. Lau PW, Guiley KZ, De N, Potter CS, Carragher B, MacRae IJ. The molecular architecture of human Dicer. Nat Struct Mol Biol. 2012;19(4):436-40. PMCID PMC3319852. PubMed
15. Lau PW, Potter CS, Carragher B, MacRae IJ. DOLORS: Versatile Strategy for Internal Labeling and Domain Localization in Electron Microscopy. Structure. 2012;20(12):1995-2002. PMCID PMC3535077. PubMed
16. Mim C, Cui H, Gawronski-Salerno JA, Frost A, Lyman E, Voth GA, Unger VM. Structural basis of membrane bending by the N-BAR protein endophilin. Cell. 2012;149(1):137-45. PMCID PMC3319357. PubMed
17. Moeller A, Kirchdoerfer RN, Potter CS, Carragher B, Wilson IA. Organization of the influenza virus replication machinery. Science. 2012;338(6114):1631-4. PMCID PMC3578580. PubMed
18. Moeller A, Zhao C, Fried MG, Wilson-Kubalek EM, Carragher B, Whiteheart SW. Nucleotide-dependent conformational changes in the N-Ethylmaleimide Sensitive Factor (NSF) and their potential role in SNARE complex disassembly. J Struct Biol. 2012;177(2):335-43. PMCID PMC3382979. PubMed
19. Patwardhan A, Carazo JM, Carragher B, Henderson R, Heymann JB, Hill E, Jensen GJ, Lagerstedt I, Lawson CL, Ludtke SJ, Mastronarde D, Moore WJ, Roseman A, Rosenthal P, Sorzano CO, Sanz-Garcia E, Scheres SH, Subramaniam S, Westbrook J, Winn M, Swedlow JR, Kleywegt GJ. Data management challenges in three-dimensional EM. Nat Struct Mol Biol. 2012;19(12):1203-7. PubMed
20. Pratt AJ, Rambo RP, Lau PW, MacRae IJ. Preparation and characterization of the extracellular domain of human Sid-1. PLoS One. 2012;7(4):e33607. PMCID PMC3324469. PubMed
21. Roy A, Bhardwaj A, Datta P, Lander GC, Cingolani G. Small terminase couples viral DNA binding to genome-packaging ATPase activity. Structure. 2012;20(8):1403-13. PMCID PMC3563279. PubMed
22. Scheres SH. A Bayesian view on cryo-EM structure determination. J Mol Biol. 2012;415(2):406-18. PMCID PMC3314964. PubMed
23. Schneemann A, Speir JA, Tan GS, Khayat R, Ekiert DC, Matsuoka Y, Wilson IA. A virus-like particle that elicits cross-reactive antibodies to the conserved stem of influenza virus hemagglutinin. J Virol. 2012;86(21):11686-97. PMCID PMC3486276. PubMed
24. Veesler D, Quispe J, Grigorieff N, Potter CS, Carragher B, Johnson JE. Maturation in action: CryoEM study of a viral capsid caught during expansion. Structure. 2012;20(8):1384-90. PMCID PMC3418467. PubMed
25. Xu Y, Moeller A, Jun SY, Le M, Yoon BY, Kim JS, Lee K, Ha NC. Assembly and channel opening of outer membrane protein in tripartite drug efflux pumps of Gram-negative bacteria. J Biol Chem. 2012;287(15):11740-50. PMCID PMC3320922. PubMed
26. Zimanyi CM, Ando N, Brignole EJ, Asturias FJ, Stubbe J, Drennan CL. Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase. Structure. 2012;20(8):1374-83. PMCID PMC3459064. PubMed

2011 (23)

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2. Chandramouli P, Hernandez-Lopez R, Wang HW, Leschziner AE. Validation of the orthogonal tilt reconstruction method with a biological test sample. J Struct Biol. 2011;175(1):85-96. PubMed
3. Chappie JS, Mears JA, Fang S, Leonard M, Schmid SL, Milligan RA, Hinshaw JE, Dyda F. A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke. Cell. 2011;147(1):209-22. PMCID PMC3185303. PubMed
4. Chittuluru JR, Chaban Y, Monnet-Saksouk J, Carrozza MJ, Sapountzi V, Selleck W, Huang J, Utley RT, Cramet M, Allard S, Cai G, Workman JL, Fried MG, Tan S, Cote J, Asturias FJ. Structure and nucleosome interaction of the yeast NuA4 and Piccolo-NuA4 histone acetyltransferase complexes. Nat Struct Mol Biol. 2011;18(11):1196-203. PMCID PMC3210417. PubMed
5. Fisher LS, Ward A, Milligan RA, Unwin N, Potter CS, Carragher B. A helical processing pipeline for EM structure determination of membrane proteins. Methods. 2011;55(4):350-62. PMCID PMC3262078. PubMed
6. Ganser-Pornillos BK, Chandrasekaran V, Pornillos O, Sodroski JG, Sundquist WI, Yeager M. Hexagonal assembly of a restricting TRIM5alpha protein. Proc Natl Acad Sci U S A. 2011;108(2):534-9. PMCID PMC3021009. PubMed
7. Glaeser RM, Typke D, Tiemeijer PC, Pulokas J, Cheng A. Precise beam-tilt alignment and collimation are required to minimize the phase error associated with coma in high-resolution cryo-EM. J Struct Biol. 2011;174(1):1-10. PMCID PMC3056894. PubMed
8. Huang RK, Khayat R, Lee KK, Gertsman I, Duda RL, Hendrix RW, Johnson JE. The Prohead-I Structure of Bacteriophage HK97: Implications for Scaffold-Mediated Control of Particle Assembly and Maturation. J Mol Biol. 2011;408(3):541-54. PMCID PMC3075369. PubMed
9. Khayat R, Brunn N, Speir JA, Hardham JM, Ankenbauer RG, Schneemann A, Johnson JE. The 2.3-angstrom structure of porcine circovirus 2. J Virol. 2011;85(15):7856-62. PMCID PMC3147897. PubMed
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11. Milazzo AC, Cheng A, Moeller A, Lyumkis D, Jacovetty E, Polukas J, Ellisman MH, Xuong NH, Carragher B, Potter CS. Initial evaluation of a direct detection device detector for single particle cryo-electron microscopy. J Struct Biol. 2011;176(3):404-8. PMCID PMC3210420. PubMed
12. Neuman BW, Kiss G, Kunding AH, Bhella D, Baksh MF, Connelly S, Droese B, Klaus JP, Makino S, Sawicki SG, Siddell SG, Stamou DG, Wilson IA, Kuhn P, Buchmeier MJ. A structural analysis of M protein in coronavirus assembly and morphology. J Struct Biol. 2011;174(1):11-22. PubMed
13. Pejchal R, Doores KJ, Walker LM, Khayat R, Huang PS, Wang SK, Stanfield RL, Julien JP, Ramos A, Crispin M, Depetris R, Katpally U, Marozsan A, Cupo A, Maloveste S, Liu Y, McBride R, Ito Y, Sanders RW, Ogohara C, Paulson JC, Feizi T, Scanlan CN, Wong CH, Moore JP, Olson WC, Ward AB, Poignard P, Schief WR, Burton DR, Wilson IA. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science. 2011;334(6059):1097-103. PMCID PMC3280215. PubMed
14. Safinya CR, Raviv U, Needleman DJ, Zidovska A, Choi MC, Ojeda-Lopez MA, Ewert KK, Li Y, Miller HP, Quispe J, Carragher B, Potter CS, Kim MW, Feinstein SC, Wilson L. Nanoscale assembly in biological systems: from neuronal cytoskeletal proteins to curvature stabilizing lipids. Adv Mater. 2011;23(20):2260-70. PubMed
15. Southworth DR, Agard DA. Client-Loading Conformation of the Hsp90 Molecular Chaperone Revealed in the Cryo-EM Structure of the Human Hsp90:Hop Complex. Molecular Cell. 2011;42(6):771-81. PMCID PMC3144320 PubMed
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18. Vadia S, Arnett E, Haghighat AC, Wilson-Kubalek EM, Tweten RK, Seveau S. The pore-forming toxin listeriolysin O mediates a novel entry pathway of L. monocytogenes into human hepatocytes. PLoS Pathog. 2011;7(11):e1002356. PMCID PMC3207921. PubMed
19. Wang K, Fu CY, Khayat R, Doerschuk PC, Johnson JE. In vivo virus structures: Simultaneous classification, resolution enhancement, and noise reduction in whole-cell electron tomography. J Struct Biol. 2011;174(3):425-33. PMCID PMC3091986. PubMed
20. Xu Y, Lee M, Moeller A, Song S, Yoon BY, Kim HM, Jun SY, Lee K, Ha NC. Funnel-like hexameric assembly of the periplasmic adapter protein in the tripartite multidrug efflux pump in gram-negative bacteria. J Biol Chem. 2011;286(20):17910-20. PMCID PMC3093866. PubMed
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22. Sanz-Garcia E, Stewart AB, Belnap DM. The random-model method enables ab initio 3D reconstruction of asymmetric particles and determination of particle symmetry. J Struct Biol. 2010;171(2):216-22. PMCID PMC2885456. PubMed
23. Severcan I, Geary C, Chworos A, Voss N, Jacovetty E, Jaeger L. A polyhedron made of tRNAs. Nat Chem. 2010;2(9):772-9. PMCID PMC2928159. PubMed
24. Subramanian R, Wilson-Kubalek EM, Arthur CP, Bick MJ, Campbell EA, Darst SA, Milligan RA, Kapoor TM. Insights into antiparallel microtubule crosslinking by PRC1, a conserved nonmotor microtubule binding protein. Cell. 2010;142(3):433-43. PMCID PMC2966277. PubMed
25. Taube S, Rubin JR, Katpally U, Smith TJ, Kendall A, Stuckey JA, Wobus CE. High-resolution x-ray structure and functional analysis of the murine norovirus 1 capsid protein protruding domain. J Virol. 2010;84(11):5695-705. PMCID PMC2876589. PubMed
26. Voss NR, Lyumkis D, Cheng A, Lau PW, Mulder A, Lander GC, Brignole EJ, Fellmann D, Irving C, Jacovetty EL, Leung A, Pulokas J, Quispe JD, Winkler H, Yoshioka C, Carragher B, Potter CS. A toolbox for ab initio 3-D reconstructions in single-particle electron microscopy. J Struct Biol. 2010;169(3):389-98. PMCID PMC2826578. PubMed
27. Voss NR, Potter CS, Smith R, Carragher B. Software tools for molecular microscopy: an open-text Wikibook. Methods Enzymol. 2010;482:381-92. PubMed
28. Yoshioka C, Carragher B, Potter CS. Cryomesh: a new substrate for cryo-electron microscopy. Microsc Microanal. 2010;16(1):43-53. PMCID PMC2840046. PubMed
29. Yu Y, Smith DM, Kim HM, Rodriguez V, Goldberg AL, Cheng Y. Interactions of PAN’s C-termini with archaeal 20S proteasome and implications for the eukaryotic proteasome-ATPase interactions. Embo J. 2010;29(3):692-702. PMCID PMC2830694. PubMed

2009 (22)

1. Ambrose RL, Lander GC, Maaty WS, Bothner B, Johnson JE, Johnson KN. Drosophila A virus is an unusual RNA virus with a T=3 icosahedral core and permuted RNA-dependent RNA polymerase. J Gen Virol. 2009;90(Pt 9):2191-200. PMCID PMC2742409 PubMed
2. Brignole EJ, Smith S, Asturias FJ. Conformational flexibility of metazoan fatty acid synthase enables catalysis. Nat Struct Mol Biol. 2009;16(2):190-7. PMCID PMC2653270. PubMed
3. Chappie JS, Acharya S, Liu YW, Leonard M, Pucadyil TJ, Schmid SL. An intramolecular signaling element that modulates dynamin function in vitro and in vivo. Mol Biol Cell. 2009;20(15):3561-71. PMCID PMC2719574. PubMed
4. Elmlund D, Elmlund H. High-resolution single-particle orientation refinement based on spectrally self-adapting common lines. J Struct Biol. 2009;167(1):83-94. PubMed
5. Hudson BP, Quispe J, Lara-Gonzalez S, Kim Y, Berman HM, Arnold E, Ebright RH, Lawson CL. Three-dimensional EM structure of an intact activator-dependent transcription initiation complex. Proc Natl Acad Sci U S A. 2009;106(47):19830-5. PMCID PMC2775702. PubMed
6. Ke Y, Douglas SM, Liu M, Sharma J, Cheng A, Leung A, Liu Y, Shih WM, Yan H. Multilayer DNA origami packed on a square lattice. J Am Chem Soc. 2009;131(43):15903-8. PMCID PMC2821935. PubMed
7. Lander GC, Khayat R, Li R, Prevelige PE, Potter CS, Carragher B, Johnson JE. The P22 tail machine at subnanometer resolution reveals the architecture of an infection conduit. Structure. 2009;17(6):789-99. PMCID PMC2714705. PubMed
8. Lander GC, Stagg SM, Voss NR, Cheng A, Fellmann D, Pulokas J, Yoshioka C, Irving C, Mulder A, Lau PW, Lyumkis D, Potter CS, Carragher B. Appion: an integrated, database-driven pipeline to facilitate EM image processing. J Struct Biol. 2009;166(1):95-102. PMCID PMC2775544 PubMed
9. Lau PW, Potter CS, Carragher B, MacRae IJ. Structure of the human Dicer-TRBP complex by electron microscopy. Structure. 2009;17(10):1326-32. PMCID PMC2880462. PubMed
10. Matsui T, Lander G, Johnson JE. Characterization of large conformational changes and autoproteolysis in the maturation of a T=4 virus capsid. J Virol. 2009;83(2):1126-34. PMCID PMC2612371. PubMed
11. Mulder AM, Glavis-Bloom A, Moores CA, Wagenbach M, Carragher B, Wordeman L, Milligan RA. A new model for binding of kinesin 13 to curved microtubule protofilaments. J Cell Biol. 2009;185(1):51-7. PMCID PMC2700504. PubMed
12. Pornillos O, Ganser-Pornillos BK, Kelly BN, Hua Y, Whitby FG, Stout CD, Sundquist WI, Hill CP, Yeager M. X-ray structures of the hexameric building block of the HIV capsid. Cell. 2009;137(7):1282-92. PMCID PMC2840706. PubMed
13. Prust CJ, Doerschuk PC, Lander GC, Johnson JE. Ab initio maximum likelihood reconstruction from cryo electron microscopy images of an infectious virion of the tailed bacteriophage P22 and maximum likelihood versions of Fourier Shell Correlation appropriate for measuring resolution of spherical or cylindrical objects. J Struct Biol. 2009;167(3):185-99. PMCID PMC2803348. PubMed
14. Schafer B, Quispe J, Choudhary V, Chipuk JE, Ajero TG, Du H, Schneiter R, Kuwana T. Mitochondrial outer membrane proteins assist Bid in Bax-mediated lipidic pore formation. Mol Biol Cell. 2009;20(8):2276-85. PMCID PMC2669034. PubMed
15. Sharma J, Chhabra R, Cheng A, Brownell J, Liu Y, Yan H. Control of self-assembly of DNA tubules through integration of gold nanoparticles. Science. 2009;323(5910):112-6. PMCID PMC2893555. PubMed
16. Suloway C, Shi J, Cheng A, Pulokas J, Carragher B, Potter CS, Zheng SQ, Agard DA, Jensen GJ. Fully automated, sequential tilt-series acquisition with Leginon. J Struct Biol. 2009;167(1):11-8. PMCID PMC2724967. PubMed
17. Voss NR, Yoshioka CK, Radermacher M, Potter CS, Carragher B. DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy. J Struct Biol. 2009;166(2):205-13. PMCID PMC2768396 PubMed
18. Ward A, Mulligan S, Carragher B, Chang G, Milligan RA. Nucleotide dependent packing differences in helical crystals of the ABC transporter MsbA. J Struct Biol. 2009;165(3):169-75. PMCID PMC2703300. PubMed
19. Zidovska A, Evans HM, Ewert KK, Quispe J, Carragher B, Potter CS, Safinya CR. Liquid crystalline phases of dendritic lipid-DNA self-assemblies: lamellar, hexagonal, and DNA bundles. J Phys Chem B. 2009;113(12):3694-703. PMCID PMC2858692. PubMed
20. Zidovska A, Ewert KK, Quispe J, Carragher B, Potter CS, Safinya CR. The effect of salt and pH on block liposomes studied by cryogenic transmission electron microscopy. Biochim Biophys Acta. 2009;1788(9):1869-76. PMCID PMC2740798 PubMed
21. Zidovska A, Ewert KK, Quispe J, Carragher B, Potter CS, Safinya CR. Block liposomes from curvature-stabilizing lipids: connected nanotubes, -rods, or -spheres. Langmuir. 2009;25(5):2979-85. PMCID PMC2647992. PubMed
22. Zidovska A, Ewert KK, Quispe J, Carragher B, Potter CS, Safinya CR. Block liposomes vesicles of charged lipids with distinctly shaped nanoscale sphere-, pear-, tube-, or rod-segments. Methods Enzymol. 2009;465:111-28. PubMed

2008 (20)

1. Allred DB, Cheng A, Sarikaya M, Baneyx F, Schwartz DT. Three-Dimensional Architecture of Inorganic Nanoarrays Electrodeposited through a Surface-Layer Protein Mask. Nano Letters. 2008;8(5):1434-8. PubMed
2. Asmar-Rovira GA, Asseo-Garcia AM, Quesada O, Hanson MA, Cheng A, Nogueras C, Lasalde-Dominicci JA, Stevens RC. Biophysical and ion channel functional characterization of the Torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments. J Membr Biol. 2008;223(1):13-26. PMCID PMC2668541. PubMed
3. Carter AP, Garbarino JE, Wilson-Kubalek EM, Shipley WE, Cho C, Milligan RA, Vale RD, Gibbons IR. Structure and functional role of dynein’s microtubule-binding domain. Science. 2008;322(5908):1691-5. PMCID PMC2663340. PubMed
4. Clare DK, Stagg S, Quispe J, Farr GW, Horwich AL, Saibil HR. Multiple states of a nucleotide-bound group 2 chaperonin. Structure. 2008;16(4):528-34. PMCID PMC2719814. PubMed
5. Frost A, Perera R, Roux A, Spasov K, Destaing O, Egelman EH, De Camilli P, Unger VM. Structural basis of membrane invagination by F-BAR domains. Cell. 2008;132(5):807-17. PMCID PMC2384079. PubMed
6. Hanson JA, Chang CB, Graves SM, Li Z, Mason TG, Deming TJ. Nanoscale double emulsions stabilized by single-component block copolypeptides. Nature. 2008;455(7209):85-8. PubMed
7. Kang S, Lander GC, Johnson JE, Prevelige PE. Development of bacteriophage p22 as a platform for molecular display: genetic and chemical modifications of the procapsid exterior surface. Chembiochem. 2008;9(4):514-8. PubMed
8. Katpally U, Wobus CE, Dryden K, Virgin HWth, Smith TJ. Structure of antibody-neutralized murine norovirus and unexpected differences from viruslike particles. J Virol. 2008;82(5):2079-88. PMCID PMC2258928. PubMed
9. Lander GC, Evilevitch A, Jeembaeva M, Potter CS, Carragher B, Johnson JE. Bacteriophage lambda stabilization by auxiliary protein gpD: timing, location, and mechanism of attachment determined by cryo-EM. Structure. 2008;16(9):1399-406. PMCID PMC2614288. PubMed
10. Littlefield KP, Ward AB, Chappie JS, Reedy MK, Bernstein SI, Milligan RA, Reedy MC. Similarities and differences between frozen-hydrated, rigor acto-S1 complexes of insect flight and chicken skeletal muscles. J Mol Biol. 2008;381(3):519-28. PMCID PMC2567842. PubMed
11. Moores CA, Milligan RA. Visualisation of a kinesin-13 motor on microtubule end mimics. J Mol Biol. 2008;377(3):647-54. PMCID PMC2396873. PubMed
12. Nemecek D, Lander GC, Johnson JE, Casjens SR, Thomas GJ Jr. Assembly architecture and DNA binding of the bacteriophage P22 terminase small subunit. J Mol Biol. 2008;383(3):494-501. PMCID PMC2577774. PubMed
13. Neuman BW, Adair BD, Yeager M, Buchmeier MJ. Purification and electron cryomicroscopy of coronavirus particles. Methods Mol Biol. 2008;454:129-36. PubMed
14. Prasuhn DE Jr, Kuzelka J, Strable E, Udit AK, Cho SH, Lander GC, Quispe JD, Diers JR, Bocian DF, Potter C, Carragher B, Finn MG. Polyvalent display of heme on hepatitis B virus capsid protein through coordination to hexahistidine tags. Chem Biol. 2008;15(5):513-9. PMCID PMC2715361. PubMed
15. Smith R, Carragher B. Software tools for molecular microscopy. J Struct Biol. 2008;163(3):224-8. PMCID PMC2572711. PubMed
16. Stagg SM, Lander GC, Quispe J, Voss NR, Cheng A, Bradlow H, Bradlow S, Carragher B, Potter CS. A test-bed for optimizing high-resolution single particle reconstructions. J Struct Biol. 2008;163(1):29-39. PMCID PMC2505049. PubMed
17. Stagg SM, LaPointe P, Razvi A, Gurkan C, Potter CS, Carragher B, Balch WE. Structural basis for cargo regulation of COPII coat assembly. Cell. 2008;134(3):474-84. PMCID PMC2649882. PubMed
18. Strable E, Prasuhn DE Jr, Udit AK, Brown S, Link AJ, Ngo JT, Lander G, Quispe J, Potter CS, Carragher B, Tirrell DA, Finn MG. Unnatural amino acid incorporation into virus-like particles. Bioconjug Chem. 2008;19(4):866-75. PMCID PMC2713011. PubMed
19. Wilson-Kubalek EM, Cheeseman IM, Yoshioka C, Desai A, Milligan RA. Orientation and structure of the Ndc80 complex on the microtubule lattice. J Cell Biol. 2008;182(6):1055-61. PMCID PMC2542468. PubMed
20. Zheng H, Olia AS, Gonen M, Andrews S, Cingolani G, Gonen T. A conformational switch in bacteriophage p22 portal protein primes genome injection. Mol Cell. 2008;29(3):376-83. PubMed

2007 (17)

1. Carragher B, Potter CS, Sigworth FJ. Software tools for macromolecular microscopy. J Struct Biol. 2007;157(1):1-2. PubMed
2. Cheng A, Leung A, Fellmann D, Quispe J, Suloway C, Pulokas J, Abeyrathne PD, Lam JS, Carragher B, Potter CS. Towards automated screening of two-dimensional crystals. J Struct Biol. 2007;160(3):324-31. PMCID PMC2141647. PubMed
3. Cheng A, Yeager M. Bootstrap resampling for voxel-wise variance analysis of three-dimensional density maps derived by image analysis of two-dimensional crystals. J Struct Biol. 2007;158(1):19-32. PMCID PMC2840724. PubMed
4. Fejeran A, Palanco J, Lander G, Ajero T Jr, Carragher C, Potter CS TEM of Bacteriophages Found in Marine Sources. Microscopy Today. 2007(November 2007):28-31.
5. Ganser-Pornillos BK, Cheng A, Yeager M. Structure of full-length HIV-1 CA: a model for the mature capsid lattice. Cell. 2007;131(1):70-9. PubMed
6. Katpally U, Kakani K, Reade R, Dryden K, Rochon D, Smith TJ. Structures of T=1 and T=3 particles of cucumber necrosis virus: evidence of internal scaffolding. J Mol Biol. 2007;365(2):502-12. PubMed
7. Manuell AL, Quispe J, Mayfield SP. Structure of the chloroplast ribosome: novel domains for translation regulation. PLoS Biol. 2007;5(8):e209. PMCID PMC1939882. PubMed
8. Mizuno N, Narita A, Kon T, Sutoh K, Kikkawa M. Three-dimensional structure of cytoplasmic dynein bound to microtubules. Proc Natl Acad Sci U S A. 2007;104(52):20832-7. PMCID PMC2409227. PubMed
9. Poliakov A, van Duijn E, Lander G, Fu CY, Johnson JE, Prevelige PE Jr, Heck AJ. Macromolecular mass spectrometry and electron microscopy as complementary tools for investigation of the heterogeneity of bacteriophage portal assemblies. J Struct Biol. 2007;157(2):371-83. PubMed
10. Quispe J, Damiano J, Mick SE, Nackashi DP, Fellmann D, Ajero TG, Carragher B, Potter CS. An improved holey carbon film for cryo-electron microscopy. Microsc Microanal. 2007;13(5):365-71. PubMed
11. Scherer EM, Zwick MB, Teyton L, Burton DR. Difficulties in eliciting broadly neutralizing anti-HIV antibodies are not explained by cardiolipin autoreactivity. AIDS. 2007;21(16):2131-9. PubMed
12. Stagg SM, LaPointe P, Balch WE. Structural design of cage and coat scaffolds that direct membrane traffic. Curr Opin Struct Biol. 2007;17(2):221-8. PubMed
13. Suzuki S, Wilson-Kubalek EM, Wert D, Tsao TS, Lee DH. The oligomeric structure of high molecular weight adiponectin. FEBS Lett. 2007;581(5):809-14. PMCID PMC1865574. PubMed
14. Taylor DW, Kelly DF, Cheng A, Taylor KA. On the freezing and identification of lipid monolayer 2-D arrays for cryoelectron microscopy. J Struct Biol. 2007;160(3):305-12. PMCID PMC2268103. PubMed
15. Uchida M, Klem MT, Allen M, Suci P, Flenniken M, Gillitzer E, Varpness Z, Liepold LO, Young M, Douglas T. Biological Containers: Protein Cages as Multifunctional Nanoplatforms. Advanced Materials. 2007;19(8):1025-42. PubMed
16. Woolford D, Hankamer B, Ericksson G. The Laplacian of Gaussian and arbitrary z-crossings approach applied to automated single particle reconstruction. J Struct Biol. 2007;159(1):122-34. PubMed
17. Yoshioka C, Pulokas J, Fellmann D, Potter CS, Milligan RA, Carragher B. Automation of random conical tilt and orthogonal tilt data collection using feature-based correlation. J Struct Biol. 2007;159(3):335-46. PMCID PMC2043090. PubMed

2006 (14)

1. Cheeseman IM, Chappie JS, Wilson-Kubalek EM, Desai A. The conserved KMN network constitutes the core microtubule-binding site of the kinetochore. Cell. 2006;127(5):983-97. PubMed
2. Cheng A, Fellmann D, Pulokas J, Potter CS, Carragher B. Does contamination buildup limit throughput for automated cryoEM? J Struct Biol. 2006;154(3):303-11. PubMed
3. Endres NF, Yoshioka C, Milligan RA, Vale RD. A lever-arm rotation drives motility of the minus-end-directed kinesin Ncd. Nature. 2006;439(7078):875-8. PubMed
4. Fellmann D, Banez R, Carragher B, Potter CS. Temperature monitoring of an EM environment. Microscopy Today. 2006:24-8.
5. Gan L, Speir JA, Conway JF, Lander G, Cheng N, Firek BA, Hendrix RW, Duda RL, Liljas L, Johnson JE. Capsid conformational sampling in HK97 maturation visualized by X-ray crystallography and cryo-EM. Structure. 2006;14(11):1655-65. PubMed
6. Gurkan C, Stagg SM, Lapointe P, Balch WE. The COPII cage: unifying principles of vesicle coat assembly. Nat Rev Mol Cell Biol. 2006;7(10):727-38. PubMed
7. Lander GC, Tang L, Casjens SR, Gilcrease EB, Prevelige P, Poliakov A, Potter CS, Carragher B, Johnson JE. The structure of an infectious P22 virion shows the signal for headful DNA packaging. Science. 2006;312(5781):1791-5. PubMed
8. Mallick S, Agarwal S, Kriegman D, Belongie S, Carragher B., Potter C. Vision in the Small: Reconstructing the Structure of Protein Macromolecules from Cryo-Electron Micrographs. BMVC . 2006;I(September 2006):1-6. PubMed
9. Mallick SP, Agarwal S, Kriegman DJ, Belongie SJ, Carragher B., Potter, C.S. Structure and View Estimation for Tomographic Reconstruction: A Bayesian Approach. Computer Vision and Pattern Recongnition, IEEE Computer Society Conference on. 2006;2:2253-60.
10. Neuman BW, Adair BD, Yoshioka C, Quispe JD, Milligan RA, Yeager M, Buchmeier MJ. Ultrastructure of SARS-CoV, FIPV, and MHV revealed by electron cryomicroscopy. Adv Exp Med Biol. 2006;581:181-5. PubMed
11. Neuman BW, Adair BD, Yoshioka C, Quispe JD, Orca G, Kuhn P, Milligan RA, Yeager M, Buchmeier MJ. Supramolecular architecture of severe acute respiratory syndrome coronavirus revealed by electron cryomicroscopy. J Virol. 2006;80(16):7918-28. PMCID PMC1563832. PubMed
12. Pantelic RS, Rothnagel R, Huang CY, Muller D, Woolford D, Landsberg MJ, McDowall A, Pailthorpe B, Young PR, Banks J, Hankamer B, Ericksson G. The discriminative bilateral filter: an enhanced denoising filter for electron microscopy data. J Struct Biol. 2006;155(3):395-408. PubMed
13. Stagg SM, Gurkan C, Fowler DM, LaPointe P, Foss TR, Potter CS, Carragher B, Balch WE. Structure of the Sec13/31 COPII coat cage. Nature. 2006;439(7073):234-8. PubMed
14. Stagg SM, Lander GC, Pulokas J, Fellmann D, Cheng A, Quispe JD, Mallick SP, Avila RM, Carragher B, Potter CS. Automated cryoEM data acquisition and analysis of 284742 particles of GroEL. J Struct Biol. 2006;155(3):470-81. PubMed

2005 (5)

1. Dang TX, Farah SJ, Gast A, Robertson C, Carragher B, Egelman E, Wilson-Kubalek EM. Helical crystallization on lipid nanotubes: streptavidin as a model protein. J Struct Biol. 2005;150(1):90-9. PubMed
2. Kollman JM, Quispe J. The 17A structure of the 420 kDa lobster clottable protein by single particle reconstruction from cryoelectron micrographs. J Struct Biol. 2005;151(3):306-14. PubMed
3. Mallick SP, Carragher B, Potter CS, Kriegman DJ. ACE: automated CTF estimation. Ultramicroscopy. 2005;104(1):8-29. PubMed
4. Manuell AL, Yamaguchi K, Haynes PA, Milligan RA, Mayfield SP. Composition and structure of the 80S ribosome from the green alga Chlamydomonas reinhardtii: 80S ribosomes are conserved in plants and animals. J Mol Biol. 2005;351(2):266-79. PubMed
5. Suloway C, Pulokas J, Fellmann D, Cheng A, Guerra F, Quispe J, Stagg S, Potter CS, Carragher B. Automated molecular microscopy: the new Leginon system. J Struct Biol. 2005;151(1):41-60. PubMed

2004 (19)

1. Batters C, Arthur CP, Lin A, Porter J, Geeves MA, Milligan RA, Molloy JE, Coluccio LM. Myo1c is designed for the adaptation response in the inner ear. EMBO J. 2004;23(7):1433-40. PMCID PMC391074. PubMed
2. Carragher B, Fellmann D, Guerra F, Milligan RA, Mouche F, Pulokas J, Sheehan B, Quispe J, Suloway C, Zhu Y, Potter CS. Rapid routine structure determination of macromolecular assemblies using electron microscopy: current progress and further challenges. J Synchrotron Radiat. 2004;11(Pt 1):83-5. PubMed
3. Huang Z, Penczek PA. Application of template matching technique to particle detection in electron micrographs. J Struct Biol. 2004;145(1-2):29-40. PubMed
4. Kumar V, Heikkonen J, Engelhardt P, Kaski K. Robust filtering and particle picking in micrograph images towards 3D reconstruction of purified proteins with cryo-electron microscopy. J Struct Biol. 2004;145(1-2):41-51. PubMed
5. Mallick SP, Zhu Y, Kriegman D. Detecting particles in cryo-EM micrographs using learned features. J Struct Biol. 2004;145(1-2):52-62. PubMed
6. Moores CA, Perderiset M, Francis F, Chelly J, Houdusse A, Milligan RA. Mechanism of microtubule stabilization by doublecortin. Mol Cell. 2004;14(6):833-9. PubMed
7. O’Keefe MA, Turner J, Musante J, Hetherington C, Cullis AG, Carragher B, Jenkins R, Milgrim J, Milligan R, Potter CS, Allard L, Blom D, Degenhardt L, Sides W. Laboratory design for high-performance electron microscopy. Microscopy Today. 2004:8-14. PubMed
8. Potter CS, Pulokas J, Smith P, Suloway C, Carragher B. Robotic grid loading system for a transmission electron microscope. J Struct Biol. 2004;146(3):431-40. PubMed
9. Potter CS, Zhu Y, Carragher B. Automated particle selection for cryo-electron microscopy. Journal of Structural Biology. 2004;145(1-2):1-2. PubMed
10. Roger B, Al-Bassam J, Dehmelt L, Milligan RA, Halpain S. MAP2c, but not tau, binds and bundles F-actin via its microtubule binding domain. Curr Biol. 2004;14(5):363-71. PubMed
11. Roseman AM. FindEM–a fast, efficient program for automatic selection of particles from electron micrographs. J Struct Biol. 2004;145(1-2):91-9. PubMed
12. Shih WM, Quispe JD, Joyce GF. A 1.7-kilobase single-stranded DNA that folds into a nanoscale octahedron. Nature. 2004;427(6975):618-21. PubMed
13. Shipley K, Hekmat-Nejad M, Turner J, Moores C, Anderson R, Milligan R, Sakowicz R, Fletterick R. Structure of a kinesin microtubule depolymerization machine. Embo J. 2004;23(7):1422-32. PubMed
14. Sigworth FJ. Classical detection theory and the cryo-EM particle selection problem. J Struct Biol. 2004;145(1-2):111-22. PubMed
15. Volkmann N. An approach to automated particle picking from electron micrographs based on reduced representation templates. J Struct Biol. 2004;145(1-2):152-6. PubMed
16. Wong HC, Chen J, Mouche F, Rouiller I, Bern M. Model-based particle picking for cryo-electron microscopy. J Struct Biol. 2004;145(1-2):157-67. PubMed
17. Yu Z, Bajaj C. Detecting circular and rectangular particles based on geometric feature detection in electron micrographs. J Struct Biol. 2004;145(1-2):168-80. PubMed
18. Zhu Y, Carragher B, Glaeser RM, Fellmann D, Bajaj C, Bern M, Mouche F, de Haas F, Hall RJ, Kriegman DJ, Ludtke SJ, Mallick SP, Penczek PA, Roseman AM, Sigworth FJ, Volkmann N, Potter CS. Automatic particle selection: results of a comparative study. J Struct Biol. 2004;145(1-2):3-14. PubMed
19. Zhu Y, Carragher B, Potter CS. Contaminant detection: improving template matching based particle selection for cryo-electron microscopy. IEEE Symposium on Biomedical Imaging, Arlington, VA April 15-18, 2004. 2004:1071-74.

2003 (6)

1. Al-Bassam J, Cui Y, Klopfenstein D, Carragher BO, Vale RD, Milligan RA. Distinct conformations of the kinesin Unc104 neck regulate a monomer to dimer motor transition. J Cell Biol. 2003;163(4):743-53. PMCID PMC2173678. PubMed
2. Carragher B, Penczek PA. Analytical methods and software tools for macromolecular microscopy. J Struct Biol. 2003;144(1-2):1-3. PubMed
3. Moores CA, Hekmat-Nejad M, Sakowicz R, Milligan RA. Regulation of KinI kinesin ATPase activity by binding to the microtubule lattice. J Cell Biol. 2003;163(5):963-71. PMCID PMC2173608. PubMed
4. Mouche F, Zhu Y, Pulokas J, Potter CS, Carragher B. Automated three-dimensional reconstruction of keyhole limpet hemocyanin type 1. J Struct Biol. 2003;144(3):301-12. PubMed
5. Ward A, Moody MF, Sheehan B, Milligan RA, Carragher B. Windex: a toolset for indexing helices. J Struct Biol. 2003;144(1-2):172-83. PubMed
6. Zhu Y, Carragher B, Mouche F, Potter CS. Automatic particle detection through efficient Hough transforms. IEEE Trans Med Imaging. 2003;22(9):1053-62. PubMed

2002 (1)

1. Fellmann D, Pulokas J, Milligan RA, Carragher B, Potter CS. A relational database for cryoEM: experience at one year and 50 000 images. J Struct Biol. 2002;137(3):273-82. PubMed