“Direct Detection Device (DDD): the evolution of direct electron detection for low dose Cryo-EM”

Friday August 24, 2012

“Direct Detection Device (DDD): the evolution of direct electron detection for low dose Cryo-EM”

Dr. Robert B. Bilhorn, Direct Electron, LP

After 10 years of research and development, the revolutionary Direct Detection Device (DDD) has reached a new milestone with the release of the world’s largest direct electron camera, the DE-20. Building on the proven 12 megapixel DDD sensor and camera used by a number of leading cryo-EM labs over the last several years, the latest 20 megapixel camera system delivers optimized pixel size, unlimited movie mode, and high sensitivity and DQE performance. The talk will offer an overview of the evolution of the DDD technology, present features and specifications of the new DE-20 camera, as well as present a sampling of the latest DDD cryo-EM experimental results. ¬†Among the new results presented will be time-resolved imagery of CTF evolution in phase plate microscopy.